Skip to main content
OpenTrials
Completed

NCT Number: NCT04341766

Evolution of Pulmonary Ultrasound in Patients Hospitalized for Covid (Coronavirus Disease) 19

Clinical thoracic ultrasound plays an important role in the exploration, diagnosis and follow-up of thoracic pathologies.

The COVID (Coronavirus Disease) epidemic is leading to a large influx of patients in the emergency department with respiratory disorders. The rapid diagnosis of respiratory disorders in infected patients is important for further management.

Chest ultrasound has already demonstrated its value in the diagnosis of pneumonia in the emergency department with superiority over chest X-ray.

However, there is little data on the thoracic ultrasound semiology of viral pneumonia in general and of COVID in particular.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Pneumonia, Viral COVID-19 Coronaviridae Infections Coronavirus Infections Infections Lung Diseases Nidovirales Infections Pneumonia RNA Virus Infections Respiratory Tract Diseases Respiratory Tract Infections Virus Diseases

Age range

18 year–105 year

Sex eligibility

All sexes

Study type

Observational

Primary location

CHU Amiens, Amiens, France

Loading trial locations.

About this study

Chest ultrasound has already shown its value in the diagnosis of pneumonia in the emergency department with superiority over chest X-ray.

However, there is little data on the thoracic ultrasound semiology of viral pneumonia in general and of COVID in particular.

Peng reported data from 20 patients and compared them to chest CT. The abnormalities are a thickening of the pleuropneumonia line, an interstitial syndrome with B lines, corresponding to frosted glass opacities, confluent B lines (snowstorm appearance) corresponding to interstitial infiltrate, sub-pleural alveolar opacities corresponding to sub-pleural condensations, more frank alveolar images corresponding to alveolar opacities. A multifocal aspect was associated with involvement of more than 2 lobes. However, the frequency of these abnormalities as well as the sensitivity of the echo are not detailed in this article.

Another Italian article describes a clinical case of COVID-19 pneumonia with sub-pleural involvement and irregularity of the pleuro-pulmonary line.

Clinical thoracic ultrasound has a major potential interest during the COVID epidemic: available at the patient's bedside, avoiding the need to move around, feasible for the physician during his visit, easy to clean especially if ultraportable devices are used, fast and not exposing the staff any more than the usual clinical examination.

In order to determine whether this technique is useful in the management of infected patients or patients suspected of COVID-19 infection with respiratory signs, we propose a descriptive prospective study evaluating the ultrasound semiology of COVID-19 pneumonia and the interest of ultrasound in the evolutionary follow-up of these patients.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients admitted to hospital with proven COVID-19 infection with respiratory signs warranting a chest CT scan

Exclusion criteria

  • Patient not agreeing to have his or her data collected for the study
  • Unconscious patient

Treatment and study plan

No special intervention

Other

No special intervention : Ultrasound data will be collected

Primary outcomes

  1. Characteristics of pulmonary ultrasound for Covid-19 patients

    Time frame: Day one

    description of ultrasound abnormalities for Covid-19 patients

Secondary outcomes

  1. Characteristics of pulmonary ultrasound for Covid-19 patients

    Time frame: Day 3

    description of ultrasound abnormalities for Covid-19 patients

  2. Characteristics of pulmonary ultrasound for Covid-19 patients

    Time frame: Day 14

    description of ultrasound abnormalities for Covid-19 patients

  3. Charateristics of pulmonary CT-scan for Covid-19 patients

    Time frame: Day 1

    description of CT-scan abnormalities for Covid-19 patients

  4. Charateristics of pulmonary CT-scan for Covid-19 patients

    Time frame: Day 3

    description of CT-scan abnormalities for Covid-19 patients

  5. Charateristics of pulmonary CT-scan for Covid-19 patients

    Time frame: Day 14

    description of CT-scan abnormalities for Covid-19 patients

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Intercommunal Creteil

Other

Registry information

Official study title

Prospective Descriptive Study on the Evolution of Pulmonary Ultrasound in Patients Hospitalized for Covid19

Important dates

Study start
2020
Primary completion
2020
Study completion
2020
First posted
Apr 10, 2020
Registry last updated
Jul 17, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.