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NCT Number: NCT07631195

Evolution of Food Oral Processing Behaviours, Food Bolus Formation and Texture Preferences Between 6 to 12 Years Old and Adult Age

This cross sectional study investigates how the oral physiological changes during the period of dental transition (6-12 years old) influence on texture preferences, food oral processing behaviour and food bolus properties, for different foods varying in texture and in comparison to the adult population.

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Key information

Age range

6 year–12 year

Sex eligibility

All sexes

Study type

Observational

Primary location

UMR CSGA

Dijon, 21000, France

Location status: Recruiting

Location contact

Carole TOURNIER, PhD

PRINCIPAL_INVESTIGATOR

Carole Tournier, PhD HDR

CONTACT

[email protected]

About this study

Rationale:

Eating behaviour develops during childhood, shaping dietary habits that, in the long term, contribute to growth and health. The development of masticatory function during this period plays an important role in food preferences for different textures and in consumption during meals. Furthermore, chewing transforms food into a bolus for swallowing, and the physical properties of this bolus play a role in digestion and nutrient release. To date, very little data exists on bolus formation in children. The period from 6 to 12 years of age is an important period of maturation of masticatory function, during which the 20 primary teeth are gradually replaced by 28 permanent teeth. The impact of this dental transition on children's eating behavior and nutrition is currently poorly understood.

Objective:

The purposes of this study will to determine (1) how food texture preference, oral processing behaviour and food bolus properties evolve in children during the dental transition period and in comparison to adults (2) how these variables are associated with each other (3) how they are predicted from individual oral physiology (dentition, tongue strength, masticatory performance), food familiarity and parent-reported appetitive traits parameters.

Study design :

Ninety children (n=30 per theoretical stage of mixed dentition (first transitional stage: 6-8 years, inter-transitional stage: 8-10 years, and second transitional stage: 10-12 years)) and 30 adults (25-35 years) will be recruited . Their dentition and oral abilities (tongue strength and masticatory performance) will be characterized. Their oral processing behaviour (duration, number of chews and Oro-sensory exposure time) while consuming different foods (standard pieces of carrot, rice, cheese and biscuit) will be studied using video recordings. Food boluses will then be collected at the time of corresponding to swallowing (swallowing threshold) and characterized for their particles size and number, saliva uptake, and hardness. Texture preferences of all participants, as well as familiarity with the studied foods and the children's appetitive traits will be characterized using questionnaires.

Study population: Healthy children aged 6-8 (n=30), 8-9 (n=30), 10-12 (n=30) years old and 30 adults aged 25-35 years old. Exclusion criteria : dental and orthodontic treatment ongoing

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Being aged between 6 and 12 years old included or between 25 and 35 years old Being consumers of carrot, comté cheese, rice and biscuit

Exclusion criteria

  • No French social security coverage
  • Ongoing orthodontic and/or dental treatment
  • Oral motor difficulties
  • Food allergies
  • Diabetes

Treatment and study plan

Primary outcomes

  1. Oral processing duration (seconds)

    Time frame: Baseline (single timepoint only)

    Oral processing duration (sec) measured with video recording and automated video analysis

  2. Number of chews (chews/gram)

    Time frame: Baseline (single timepoint only)

    Number of chews measured with video recording and automated video analysis

  3. Oro-sensory exposure time (second/gram)

    Time frame: Baseline (single timepoint only)

    Oro-sensory exposure time (s/g) measured with video recording and automated video analysis

  4. Saliva uptake (%) in food bolus

    Time frame: Baseline (single timepoint only)

    Saliva uptake (%) of bolus collected at swallowing, measured from food and bolus mass (g) and dry matter (g)

  5. Bolus hardness (Newton)

    Time frame: Baseline (single timepoint only)

    Hardness (N) of bolus collected at swallowing obtained from simple compression test with texturometer compression test

  6. Average size of bolus particles (mm)

    Time frame: Baseline (single timepoint only)

    Size of the particles (mm) measured from a scan of the bolus diluted in glycerol and automated image analysis

  7. Number of particles in the food bolus

    Time frame: Baseline (single timepoint only)

    Number of bolus particles measured from a scan of the bolus diluted in glycerol and automated image analysis

Secondary outcomes

  1. Number of Posterior Functional Unit (PFU)

    Time frame: Baseline (single timepoint only

    Number of teeth stained after biting down on blue paper (3 times) measured by visual assessment

  2. Number of teeth

    Time frame: Baseline (single timepoint only

    Total number of teeth in the mouth measured from visual assessment

  3. Dental transition stage

    Time frame: Baseline (single timepoint only)

    Stage of primary dentition (first transitional stage, inter-transitional stage and second transitional stage) assessed from teeth photographs by dental professionals

  4. Tongue strength (kPa)

    Time frame: Baseline (single timepoint only

    Maximum strength (kPa) measured with the Iowa Oral Pressure Instrument (IOPI)

  5. Masticatory performance (index)

    Time frame: Baseline (single timepoint only)

    Ability to mix two colored chewing gum after 15 chewing cycles, measured with gum scan and automated image analysis

  6. BMIz

    Time frame: Baseline (single timepoint only)

    BMI z-scores (BMIz) obtained from body weight (kg; measured using a weighing scale) and height (cm; measured using a stadiometer) transformed into corrected for age and sex according to the WHO child growth reference for school-aged children and adolescents

  7. Food frequency consumption (child report)

    Time frame: Baseline (single timepoint only)

    Child oral self-report of consumption frequency of offered food consumption ('not at all'; 'from time to time'; 'often'; 'very often')

  8. Food frequency consumption (parental report)

    Time frame: Baseline (single timepoint only)

    Parent report on the consumption frequency by the child for the offered food. Report collected in questionnaire ('never'; 'less than once a month'; 'two to three times a month'; 'once a week'; 'two to four times a week'; 'once a day'; and 'two or more times a day')

  9. Food familiarity

    Time frame: Baseline (single timepoint only)

    Oral self-report of the familiarity with the offered food (0 : not familiar/1 : familiar)

  10. Food chewing difficulty

    Time frame: Baseline (single timepoint only)

    Oral self-report whether the offered foods is or not difficult to eat (0 : not difficult/1 : difficult)

  11. Food texture preferences

    Time frame: Baseline (single timepoint only)

    Self-report on a food texture preference questionnaire. The questionnaire is composed of 17 pairs of soft/smooth and hard/particulate foods. For each pair, the participant chose the preferred one (forced-choice). Soft/Smooth versions will have a value of 1 and hard/particulate version a value of 2. Cumulation of the values provides a Texture preference index. Higher score means higher preference for textured foods.

  12. Children chewing abilities

    Time frame: Baseline (single timepoint only)

    Parent-reports of their child chewing abilities using a questionnaire (Schwartz et al., 2021).

    The questionnaire is composed of 5 questions. Parents answer by one of the 'yes', 'no' and 'I don't know'. Questions are grouped in two dimensions

    : 'difficulty of coping with hard/difficult textures' (higher score means lower difficulty) 'extend to which children chew their food before swallowing' (the higher the score, the better the child chews the food before swallowing)

  13. Child Eating Behaviour and Appetitive traits

    Time frame: Baseline (single timepoint only)

    Parent-reports on the Child Eating Behaviour Questionnaire (CEBQ) will be used to characterize the appetitive traits of the participants (Wardle et al., 2001). The questionnaire is composed of 35 items. Parent answers to each item using 5- point Likert scale ranging from never (1) to always (5) (never, rarely, sometimes, often, always. The items are then grouped to define 8 dimensions: 'food responsiveness', 'enjoyment of food', 'emotional over-eating', 'desire to drink', 'satiety responsiveness', 'slowness in eating', 'emotional undereating' and 'food fussiness'. Higher scores mean higher behaviours.

Study contacts

Contact information is provided by the study sponsor or research team.

Carole Tournier, PhD

CONTACT

[email protected]

0033380693077

Sponsors and collaborators

Lead sponsor

Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement

Other

Registry information

Official study title

Rôle de la Texture Des Aliments et du Comportement Masticatoire Dans Les propriétés du Bol Alimentaire et la Perception Sensorielle Chez Les Enfants d'âge Scolaire (6 à 12 Ans) en Comparaison à un Groupe Adulte

Acronym: MARELLE

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Jun 5, 2026
Registry last updated
Jun 5, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.