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OpenTrials
Completed

NCT Number: NCT02348671

Evaluation of Wound Dressings in the Reduction of Shear- Force

The purpose of this study is to investigate if wound dressings are capable in reducing the effects of shear- force at the skin. With our own shear- force model we are able to apply 19 Newton shear- force combined with 9 newton pressure at the skin of the non- dominant forearm. After half an hour we measure IL-1alpha/ total protein- ratio, cutaneous blood flow (Laser doppler, Moor LDI) and the erythema index (DSMIIColormeter) which occurs as an effect of shear- force application at the skin.

Then, we apply 19 Newton shear- force combined with 9 Newton pressure at the dominant fore-arm but this time we put a wound dressing between the skin and shear- force model. After half an hour we measure the IL-1alpha/total protein-ratio, cutaneous blood flow and the erythema index.

This research consists of three research day, each day we are going to investigate a different wound dressing

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Key information

Conditions

Pressure Ulcer Skin Diseases Skin Ulcer Skin and Connective Tissue Diseases

Age range

18 year–30 year

Sex eligibility

Male

Study type

Observational

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • healhty volunteer
  • age 18- 30
  • BMI 20- 30

Exclusion criteria

  • Trauma fore-arms
  • Diabetes mellitus type I or type II
  • The use of NSAID's in the last 7 days
  • Vascular diseases
  • Muscular dystrophy
  • Malignancy
  • Participant is unable to give informed consent

Treatment and study plan

shear- force

Other

19 Newton shear- force and 3,9 kPa pressure for half an hour

Primary outcomes

  1. Cutaneous blood flow, erythema index, IL-1alpha/Total protein ratio

    Time frame: Directly after intevention

Sponsors and collaborators

Lead sponsor

Maastricht University Medical Center

Other

Registry information

Official study title

Evaluation of Wound Dressings to Reduce the Harmful Effects of Shear- Force at the Skin

Important dates

Study start
2015
Primary completion
2015
Study completion
2015
First posted
Jan 28, 2015
Registry last updated
Sep 23, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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