Evaluation of Two Enteral Nutrition Strategies in Mechanically Ventilated Patients

The aim of this study is to compare two strategies of early enteral nutrition in terms of efficacy and complications in mechanically ventilated patients.

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Key information

Conditions

Mechanically Ventilated Patients

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Service de Réanimation, Angoulême, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Adult (> 18 ans)
Mechanical ventilation for > 72 hours
Planned enteral nutrition
Informed consent

Exclusion criteria

Body Mass Index < 20 kg/m2
Enteral nutrition non indicated (ileus, splanchnic ischemia..)
Shock (use of catecholamines, arterial blood pressure < 90 mmHg, peripheral hypoperfusion, elevation of lactates > x 1,5 normal value)
Contraindications for gastric tube
Pregnancy
Previous enrollment in the present study

Treatment and study plan

Enteral nutrition

Device

Primary outcomes

Incidence of nutrition failure (diarrhea, ileus, vomiting, aspiration pneumonia, elevated residual gastric volume)

Secondary outcomes

-Measured nutrition amount when compared to theorical nutrition during ICU stay
-Measured nutrition amount when compared to theorical nutrition during the first three days
-Influence of prokinetic drugs on nutrition quality

Sponsors and collaborators

Lead sponsor

University Hospital, Limoges

Other

Registry information

Important dates

Study start: 2002
Primary completion: 2008
Study completion: 2008
First posted: Sep 20, 2005
Registry last updated: Jun 9, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed