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Active, Not Recruiting

NCT Number: NCT06855940

Evaluation of Tooth Sensitivity and Whitening Effects of Different Content Teeth Whitening Agents

The goal of this clinical study is to evaluate the success of different whitening agents in whitening teeth in healthy volunteers aged 18-50. Also, patients' tooth sensitivity will be assessed after application. The main questions it aims to answer are:

Is the teeth whitening success of different whitening agents similar? Did participants develop tooth sensitivity to whitening agents? The researchers will compare the whitening success of 3 different whitening agents and changes in tooth sensitivity within 1 year after application.

Participants:

Whitening agent will be applied in the clinic Visit our clinic for checkups and records after 1 week, 2 weeks, 1 month, 2 months, 4 months , 6 months and 1 year after application

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Erciyes University

Kayseri, Melikgazi, 38000, Turkey (Türkiye)

About this study

The participants in the study were healthy volunteers between the ages of 18-50. The number of volunteers was determined by using other studies similar to this study. There are 60 volunteers in three groups, 20 volunteers in each group. A different whitening agent is applied to each group by the researcher.

The researcher did not include volunteers with poor oral hygiene, smoking, tooth sensitivity, caries, or medication use in the study.

The researcher began the study by performing color measurement and sensitivity assessment before the procedure. Then he applied the whitening agent. The volunteers who underwent the whitening procedure will be evaluated in terms of both color measurements and sensitivity changes at the end of the treatment, 1st week, 2nd week, 1st month, 2nd month, 4th month, 6th month, and 1st year control sessions.

Each patient has their own evaluation form. There are different fields for both color and sensitivity in the form according to the control dates. All numerical data are recorded in their own fields.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Vital teeth
  • Healthy gums
  • No tooth sensitivity
  • External discoloration ( tea,coffee..)
  • Good oral hygiene
  • No allergy to the material to be used

Exclusion criteria

  • Decayed and devital teeth
  • Presence of gingival bleeding
  • History of trauma
  • Presence of fractures, cracks and aesthetic restoration
  • Smoking

Treatment and study plan

Bleaching Agents

Other

whitening agent containing fluoride and 40% hydrogen peroxide

Primary outcomes

  1. Change in tooth color within 1 year after whitening

    Time frame: through study completion, an average of 1 year

    Measurement and recording of numerical values of tooth color with vita easyshade device

  2. Change in tooth sensitivity after whitening within 1 year

    Time frame: through study completion, an average of 1 year

    Numerical measurement of sensitivity after bleaching with VAS (visual analog scale)

Sponsors and collaborators

Lead sponsor

Betül Tokat

Other

Collaborators

  • Scientific Research Projects
  • TC Erciyes University

Registry information

Official study title

Evaluation of the Tooth Sensitivity and Whitening Effects of Calcium, Hydroxyapatite and Fluoride Containing Tooth Whitening Agents

Important dates

Study start
2024
Primary completion
2024
Study completion
2025
First posted
Mar 4, 2025
Registry last updated
Mar 4, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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