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OpenTrials
Completed

NCT Number: NCT06180473

Evaluation of Tolerability, Efficacy and Adherence to Treatment With Wynzora Cream

The primary objective is to assess with the PPQ questionnaire the patient preference for Wynzora compared with therapy carried out previously with Enstilar spray foam. Secondary objectives Assess satisfaction with the treatment. Assess adherence to therapy. Evaluate the impact of various clinical and demographic factors on treatment adherence. Evaluate the efficacy of Wynzora cream therapy.

Completed

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Policlinico Agostino Gemelli

Rome, Italy

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients older than 18 years of age, of either sex;
  • Patients diagnosed with mild-to-moderate psoriasis (PASI and BSA <10) requiring monotherapy topical with Wynzora;
  • Patients who have stopped treatment with Enstilar foam for any reason for at least 30 days; and
  • Patients whose medical records are accessible and record all demographic parameters, anthropometric and clinical parameters during the treatment period
  • Signature of written informed consent;

Exclusion criteria

  • Patients with palmoplantar, inverse, erythrodermic, guttate, and scalp psoriasis.
  • Patients who are taking concomitant systemic therapies for psoriasis, such as. cyclosporine, methotrexate, acitretin, phototherapy or biologic therapies.
  • Women who are pregnant or planning to become pregnant.
  • Patients with disabilities or other motor problems that could complicate self-medication.

Treatment and study plan

Questionnaire

Other

PPQ, TTAQ PTCS

Primary outcomes

  1. preference of wynzora cream

    Time frame: 1 month

    Percentage of patients who prefer treatment with Wynzora compared with treatment with Enstilar at week 4 of use; preference for Wynzora will be assessed by considering a score of 3 or higher on question 5 of the PPQ questionnaire.

Sponsors and collaborators

Lead sponsor

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Other

Registry information

Official study title

Evaluation of Tolerability, Efficacy and Adherence to Treatment With Wynzora Cream in Patients With Psoriasis Previously Treated With Enstilar Foam.

Acronym: psowyn

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Dec 22, 2023
Registry last updated
Sep 2, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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