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NCT Number: NCT06455943

Evaluation of Thriving, Substance Use, Mental Health, and Repeat Injury Among Participants in the THRIVE Program

The goal of this observational study is to determine the impact of a hospital-based violence intervention program on a person's capacity to thrive and recurrent intentional injury. The aims of this study are:

1. To evaluate the impact of the HVIP on building personal capacity of youth who have experienced non-fatal violent injuries to thrive using:

* Established measure changes in positive psychology and clinical metrics * A qualitative interview using thematic content analysis 2. Plot the methodology proposed to measure the impact of THRIVE on subsequent injuries using administrative data sources

Participants will complete surveys, participate in a semi-structured interview, and have their rate of recurrent intentional injury tracked over time.

Researchers will compare the rates of intentional reinjury between participants in the THRIVE program and those who present at other hospitals with similar injuries to see if there is a difference in the rate of recurrent intentional injury a 1, 5, and 10 years.

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Key information

Conditions

Age range

14 year–29 year

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • ages 14-29
  • presentation with an injury due to violence (defined as a gun shot wound, stab wound, blunt or bodily force, inflicted by someone else)
  • participant in the THRIVE Program

Exclusion criteria

  • unable to consent due to language barrier or brain injury
  • sexual assault
  • child abuse
  • self-inflicted injury
  • residence >1 hour from Toronto city limits

Treatment and study plan

Primary outcomes

  1. To evaluate the impact of the HVIP on building personal capacity of youth who have experienced non-fatal violent injuries to thrive.

    Time frame: July 2024 - December 2025

    To evaluate changes in thriving, substance use, and mental health, validated measures and qualitative measures will be used. Quantitative measures collected using validated instruments will provide objective measures of change over time; while context-specific and nuanced growth will be captured through a semi-structured interview.

  2. To pilot the methodology proposed to measure the impact of THRIVE on subsequent injuries within 1 year using administrative data sources

    Time frame: March - Sept 2026

    After 1.5 years of enrolment in THRIVE, study participants will be deterministically linked. Linkage will provide a wealth of baseline characteristics (demographics, income/marginalization), injury characteristics (ICD-10 coding patterns which can be contrasted to THRIVE documentation), as well as the capacity to follow these linked patients administratively over time and identify subsequent ED presentations and admission across any hospital in Ontario.

Study contacts

Contact information is provided by the study sponsor or research team.

Jennifer Dekker, MSc

CONTACT

[email protected]

437-331-8644

Sponsors and collaborators

Lead sponsor

Unity Health Toronto

Other

Registry information

Official study title

Evaluation of Thriving, Substance Use, Mental Health and Repeat Injury Among Participants in the THRIVE Program

Important dates

Study start
2024
Primary completion
2026
Study completion
2035
First posted
Jun 13, 2024
Registry last updated
Jun 13, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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