Evaluation of the Therapeutic Approach of Aromatherapy by Olfaction of Essential Oils in Association With Hypnosis in the Management of Patients Followed for Cancer

Include (V0):

Patients in whom the following procedures must be performed:

• Blood samples via a central catheter with a percutaneous implantable chamber, with a Huber needle
• Peripheral venous samples
• Tumor Lesion Dressing
• Complete toilet in bed will be identified by the team of the medical oncology department. During the first contact (V0), the study will be presented to the patients in order to obtain their consent. After signing the consent and before performing the gesture causing discomfort (gesture No.1), anxiety and well-being will be assessed by the verbal administration of the ESAS scale. The gesture will then be performed and the patient's comfort will be assessed using the ESAS scale after the gesture has been performed in order to obtain the data at the start of the study. An appointment for the V1 visit (between 1 and 9 days after D0) will be set for the next procedure.

First V1 hypnosis session (between 1 and 9 days after D0):

During the second contact at visit V1 (between 1 and 9 days after D0), anxiety and well-being will be assessed before performing the gesture causing discomfort (gesture No.2). Randomization will take place immediately before performing the procedure. After randomization, the first session of hypnosis +/- aromatherapy will be performed at the same time as gesture No. 2 and the patient's comfort will be evaluated after the gesture is performed. During this hypnosis session, the patient will receive self-hypnosis training according to the group they belong to (self-hypnosis vs self-hypnosis + aromatherapy). An appointment for the realization of the next gesture (gesture No.3) will be set for D7 (+/- 2 days after V1). This period of time (7±2 days) will be considered the learning time for self-hypnosis.

Second V2 hypnosis session (D7+-/ 2 days after V1):

The third contact V2 will take place at (D7+/- 2 days after V1). During this visit, anxiety and well-being will be assessed before performing the gesture causing discomfort (gesture No.3). Gesture No.3 will be carried out under the effect of self-hypnosis ± aromatherapy and the measurement of comfort will be carried out immediately afterwards.

Inclusion criteria

• Patients aged ≥18 years
• Patients followed in medical oncology and by the mobile palliative care support team
• From the first line of chemotherapy
• Patient requiring one of the following procedures:
• Blood samples via a central catheter with a percutaneous implantable chamber, with a Huber needle
• Peripheral venous samples
• Change of dressing for cancerous lesion
• Complete toilet in bed
• Patients who have given their consent
• Patient affiliated with a social security scheme

Exclusion criteria

• Protected person under guardianship or curatorship,
• Person deprived of liberty
• Person unable to express consent
• Pregnant woman and breastfeeding woman
• History of allergy or intolerance to essential oils
• Patients with cognitive or language disorders that make it impossible to answer the questionnaires
• Psychotic disorders