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OpenTrials
Completed

NCT Number: NCT05973435

Evaluation of the Level of Oxidative Stress in Relation to the Type of Anesthesia in Parturients Whose Delivery Was Completed by Caesarean Section

The goal of this observational study is to assess the level of oxidative stress during cesarean section depending on the type of anesthesia applied and to determine the factors that can affect the level of oxidative stress.

The main questions it aims to answer are:

* is there any association between specific parameters of pregnancy, socio-demographic characteristics and laboratory analyses with an increased level of oxidative stress * is there any association between type of anesthesia for ceasarean section with an increased level of oxidative stress

Blood sample would be taken from the participants in the study for these analyses on three occasions in 3 test tubes (before cesarean section, during cesarean section and after cesarean section).

Researchers will compare patients that received general anesthesia with patients under spinal regional anesthesia to see if there is any difference in level of oxidative stress measured by laboratory parameters.

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Key information

Age range

18 year–55 year

Sex eligibility

Female

Study type

Observational

Primary location

Clinical Hospital Center "Dr. Dragisa Misovic, Dedinje"

Belgrade, 11000, Serbia

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • ASA status I and II

Exclusion criteria

  • ASA status III and IV
  • Emergency C section

Treatment and study plan

Blood sampling

Other

Blood sample would be taken from the participants in the study for these analyses on three occasions in 3 test tubes (before cesarean section, during cesarean section and after cesarean section).

Primary outcomes

  1. Elevated level of oxidative stress

    Time frame: 2 hours after C section

    We will measure enzymes of oxidative stress before cesarean section, during cesarean section and after cesarean section.

Secondary outcomes

  1. Lactate level

    Time frame: 2 hours after C section

    We will measure lactate levels before cesarean section, during cesarean section and after cesarean section.

  2. Level of cortisol

    Time frame: 2 hours after C section

    We will measure cortisol levels before cesarean section, during cesarean section and after cesarean section.

Sponsors and collaborators

Lead sponsor

University Clinic Dr Dragisa Misovic-Dedinje

Other

Registry information

Important dates

Study start
2023
Primary completion
2023
Study completion
2023
First posted
Aug 2, 2023
Registry last updated
Dec 4, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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