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OpenTrials
Completed

NCT Number: NCT01465282

Evaluation of the Efficacy, Safety and Toleration of CT327 Ointment in Patients With Psoriasis Vulgaris

The purpose of this study is to evaluate the effectiveness of 3 dose strengths of CT327 ointment (0.05%, 0.1% and 0.05% w/w) compared to a placebo, when applied twice daily for up to 8 weeks, to the psoriatic plaques of patients with psoriasis vulgaris.

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Key information

Conditions

Psoriasis Vulgaris

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

Birmingham, United Kingdom

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Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Male and female subjects aged at least 18 years.
  • Stable psoriasis vulgaris

Exclusion criteria

  • Subjects with guttate, erythrodermic, exfoliative or pustular psoriasis.

Treatment and study plan

CT327 0.05%

Drug

0.05% CT327 (w/w) ointment

CT327 0.1%

Drug

0.1% CT327 (w/w) ointment

CT327 0.5%

Drug

0.5% CT327 (w/w) ointment

Placebo

Drug

Placebo

Primary outcomes

  1. Efficacy of CT327 ointment (0.05%, 0.1% and 0.5% w/w) compared with placebo ointment.

    Time frame: Week 8

Secondary outcomes

  1. Local and systemic toleration

    Time frame: 8 weeks

Sponsors and collaborators

Lead sponsor

Creabilis SA

Industry

Registry information

Official study title

A Randomized, Placebo-controlled, Phase IIb Study to Evaluate the Efficacy, Safety and Tolerability of 0.05%, 0.1% and 0.5% w/w Topical CT327 When Applied Twice Daily in Subjects With Psoriasis Vulgaris

Important dates

Study start
2011
Primary completion
2012
Study completion
2012
First posted
Nov 4, 2011
Registry last updated
Mar 8, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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