Groupe Hospitalier Paris Saint Joseph
Paris, Île-de-France Region, 75014, France
NCT Number: NCT05900063
Glaucoma is a common, potentially blinding pathology, threatening patients' autonomy and quality of life. The main aim of treatment is to lower intraocular pressure (IOP) in order to slow nerve fiber loss as much as possible, leading to alterations in the visual field and even reduced visual acuity. To achieve this drop in pressure, there are, of course, hypotonizing eye drops, trabeculoplasty with Laser Selecta (SLT) or filtering surgery (trabeculectomy, deep non-perforating sclerectomy, insertion of drainage devices). Laser Selecta specifically targets pigmented trabecular meshwork cells without damaging adjacent structures, and is thought to act via three mechanisms: distension of Schlemm's canal, reorganization of trabecular meshwork cells and stimulation of extracellular matrix production. Its efficacy has been demonstrated in several studies, with a 20-30% reduction in intraocular pressure in patients who have never undergone surgery. Few studies have investigated the efficacy of SLT in patients who have already undergone filtering surgery. The aim of this study is therefore to determine the efficacy of SLT in previously operated patients whose intraocular pressure remains insufficiently controlled.
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Notify Me18 year and older
All sexes
Observational
Paris, Île-de-France Region, 75014, France
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
- Patients under guardianship or curatorship
Time frame: 12 months
Intraocular pressure is measured before procedure , 1 month, 6months and 12 months after procedure
Time frame: 12 months
Intraocular pressure is measured before procedure , 1 month, 6months and 12 months.
average IOP decrease is calculated for the group of patients with an initial IOP >21mmHg and for the group with an initial IOP<21mmHg
Time frame: 12 months
Intraocular pressure is measured before procedure , 1 month, 6months and 12 months.
average IOP decrease is calculated for the group of patients with a less than 1 year between filtering surgery and SLT , the group with a period of 1 to 5 years between filtering surgery and SLT and the group with more than 5 year inbetween.
Time frame: 12 months
Intraocular pressure is measured before procedure , 1 month, 6months and 12 months.
average IOP decrease is calculated for each type of filtering surgery : trabeculectomy or, deep non-perforating sclerectomy, or insertion of drainage devices
Time frame: 12 months
Intraocular pressure is measured before procedure , 1 month, 6months and 12 months.
average IOP decrease is calculated for each type of glaucoma : primary open-angle glaucoma, or exfoliative glaucoma or pigmentary glaucoma
Fondation Hôpital Saint-Joseph
Other
Acronym: SLT
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