Pamukkale University Faculty of Dentistry Department of Periodontology
Denizli, 20070, Turkey (Türkiye)
Completed
NCT Number: NCT05386667
Evaluation of the Effects of Medicaments Used After Free Gingival Graft on Postoperative Complications.
In our study, three different medicaments were evaluated in terms of postoperative complications after free gingival grafting (FGG).
Completed
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Conditions
Age range
18 year and older
Sex eligibility
All sexes
Study type
Observational
Primary location
About this study
In our study, three different medicaments were evaluated in terms of postoperative complications after free gingival grafting. The effectiveness of these 3 different commercially available agents containing flurbiprofen, hyaluronic acid, and hypochlorous acid, after use 2., 4.7. and on the 14th day, wound healing and pain perception was compared with the control group. primary observation was obtained by visual analog scale, wound healing index, bleeding of tissue, color match, and amount of painkiller used by the patient were also recorded
Who can participate
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- Patients with systematic conditions are classified as The American Society of Anesthesiologists Class I
-
Exclusion criteria
- Pregnancy, lactation, and taking contraceptive pills.
- Oversensitivity or anaphylactic reactions which contraindicate the intervention.
- Orofacial neurological symptoms.
- Infections at operation zone.
- Psychotropic medicine, sedative, or non-steroid anti-inflammatory drugs use which can alter the sense of pain.
- Pathological mental conditions (dementia, psychosis) and lack of cooperation.
- Smoking
- Excessive gag reflex
- Operations are carried out with conscious sedation.
- Patients who do not want to sign consent.
Treatment and study plan
Majezik %0.25 oral spray
DrugFree gingival graft was taken from the palatal mucosa of the patients in order to increase the attached gingiva.
After FGG, the patients were asked to apply this spray to the palatal mucosa 3 times a day.
Other names: Free gingival graft harvesting
Aftamed oral spray
OtherFree gingival graft was taken from the palatal mucosa of the patients in order to increase the attached gingiva.
After FGG, the patients were asked to apply this spray to the palatal mucosa 3 times a day.
Other names: Free gingival graft harvesting
Crystalin oral spray
OtherFree gingival graft was taken from the palatal mucosa of the patients in order to increase the attached gingiva.
After FGG, the patients were asked to apply this spray to the palatal mucosa 3 times a day.
Other names: Free gingival graft harvesting
Free gingival graft harvesting
ProcedureFree gingival graft was taken from the palatal mucosa of the patients in order to increase the attached gingiva.
Primary outcomes
-
Landry's Wound Healing Index (WHI)
Time frame: 21 days
WHI was performed on the basis of postoperative healing characteristics categorized as tissue color, response to palpation, incision margins, and suppuration.
Secondary outcomes
-
Visual Analogue Scale
Time frame: 21 days
Recording the pain perception of the patients on a scale from 0 to 10. 0 - no pain 10 - worst pain
-
Color match
Time frame: 21 days
scoring the color match of the healed tissue area with the patient's remaining tissue
-
delayed bleeding
Time frame: 21 days
examining the patient whether there is postoperative bleeding, if there is a positive, if not, it should be recorded as negative.
-
burning sensation
Time frame: 21 days
Evaluation of the burning sensation felt in the healing area of the patient's palate from 0 to 10. 0-no burning sensation 10- excessive burning
-
complete epithelization
Time frame: 21 days
Examination of epithelialization with 3% oxygenated water. keeping records according to the foaming rate in the tissue
Sponsors and collaborators
Lead sponsor
Pamukkale University
Other
Registry information
Important dates
- Study start
- 2019
- Primary completion
- 2022
- Study completion
- 2022
- First posted
- May 23, 2022
- Registry last updated
- May 23, 2022
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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