Evaluation of the Effectiveness of the Ezisurg Stapling (Ezi Endo Lite) During Laparoscopic Nissen Sleeve Gastrectomy

Inclusion criteria

• Body Mass Index (BMI) ≥ 30 kg/m² (or BMI ≥ 27 kg/m² with at least one obesity-related comorbidity, e.g., type 2 diabetes, hypertension, dyslipidemia).
• Medically eligible for laparoscopic sleeve gastrectomy (LSG) or Nissan sleeve surgery, as determined by a multidisciplinary bariatric team (e.g., surgeon, endocrinologist, dietitian).
• Ability to understand and voluntarily sign written informed consent.
• Willingness to comply with post-operative follow-up protocols (e.g., dietary monitoring, clinical visits, laboratory tests).

Exclusion criteria

• BMI < 30 kg/m² (or < 27 kg/m² without obesity-related comorbidities).
• Contraindications to laparoscopic surgery (e.g., severe abdominal adhesions, hemodynamic instability, uncorrected coagulopathy).
• History of major gastrointestinal surgery (e.g., gastric bypass, colectomy) or anatomical abnormalities precluding sleeve gastrectomy.
• Active or uncontrolled chronic diseases (e.g., end-stage renal disease, cirrhosis, metastatic cancer, severe cardiovascular disease).
• Psychiatric disorders limiting adherence to post-operative care (e.g., severe depression, psychosis, substance use disorder).
• Pregnancy or breastfeeding (or plans for pregnancy within 12 months post-surgery).
• Allergy or intolerance to surgical materials, anesthesia, or post-operative medications required for the study.
• Inability to communicate or cooperate with study procedures (e.g., language barriers, cognitive impairment).