Skip to main content
OpenTrials
Completed

NCT Number: NCT06484231

Evaluation of the Effectiveness of Prophylactic LMWH by Thromboelastography

This study aims to evaluate the necessity and effectiveness of using low molecular weight heparin (LMWH) for prophylaxis in the postoperative period in patients who underwent lobectomy due to malignancy, using thromboelastography.Blood samples taken from the patients before low molecular weight heparin prophylaxis (preoperative), before prophylaxis in the postoperative period (postoperative day 1) and after the start of postoperative prophylaxis (postoperative day 3) will be examined by thromboelastography.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Malignancy Neoplasms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Ege University Faculty of Medicine

Izmir, Bornova, 35100, Turkey (Türkiye)

About this study

General characteristics of the patients such as age, gender, presence of comorbidities, smoking, type of operation and approach applied, operation duration, TEG measurements and postoperative complication development were recorded with case forms.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients who underwent lobectomy with thoracotomy or videothoracoscopy (VATS) due to malignancy (primary or secondary lung cancer)

Exclusion criteria

  • Patients with a known diagnosis of bleeding or coagulation disorders
  • Patients receiving anticoagulant and antiplatelet therapy in the preoperative period
  • Patients who developed perioperative bleeding and therefore underwent perioperative blood and blood product replacement

Treatment and study plan

Primary outcomes

  1. r time

    Time frame: 24 months

    'r time' value measured by thromboelastography

  2. k time

    Time frame: 24 months

    'k time' value measured by thromboelastography

  3. maximum amplitude (MA)

    Time frame: 24 months

    'MA' value measured by thromboelastography

  4. angle a

    Time frame: 24 months

    'angle a' value measured by thromboelastography

Secondary outcomes

  1. complications

    Time frame: 24 months

    development of complications

Sponsors and collaborators

Lead sponsor

Ege University

Other

Registry information

Official study title

Evaluation of the Effectiveness of Prophylactic Low Molecular Weight Heparin by Thromboelastography in Patients Who Underwent Lobectomy Due to Malignancy

Important dates

Study start
2023
Primary completion
2025
Study completion
2025
First posted
Jul 3, 2024
Registry last updated
Aug 12, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.