Chinese PLAGH Hospital
Beijing, Beijing Municipality, China
Location status: Recruiting
NCT Number: NCT04441151
Evaluation of the effect of pulmonary rehabilitation on patients with high flow oxygen therapy
Interested in participating?
Request Info18 year–100 year
All sexes
Interventional
Not applicable
Beijing, Beijing Municipality, China
Location status: Recruiting
Objective: the purpose of this study was to evaluate the effect of lung rehabilitation on patients treated with high flow humidification apparatus in ICU. Methods: 70 patients in ICU who were treated with high flow humidification apparatus from June 2019 to June 2020 were randomly divided into two groups. The experimental group was treated with pulmonary rehabilitation and the control group was treated with routine medical treatment only. All patients were evaluated and measured by bedside diaphragm ultrasound. The vital signs of all patients were monitored every day. MRCsum assessment of peripheral muscle strength, 30s sitting test, modified Barthel index, Borg dyspnea score, arterial blood gas analysis and bedside diaphragm ultrasound monitoring were performed at admission and discharge. Finally, statistics were made on the use of non-invasive ventilator, endotracheal intubation, new complications (pressure sore, aspiration, thrombus, etc.) and the time of patients getting out of bed for the first time.The end point of the experiment was 28 days.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Comprehensive interventions based on comprehensive evaluation and customization of patients, including, but not limited to, exercise training, education and behavioral changes, aimed at improving the physiological and psychological status of patients with chronic respiratory diseases, and urge patients to adhere to health promotion activities for a long time.
Time frame: Day 28
Medical Research Council,Muscle strength assessment,total points0~60,less than 48scores means ICU aquired weaknesses.
Time frame: Day 28
Number of sit-to-stand test in 30s,Muscle endurance assessment,The more times, has the better muscular endurance.
Time frame: Day 28
barthel index,Daily activity assessment,Assessment of activities of daily living.total points0~100,less than 60 scores means can't independent living.
Time frame: Day 28
Borg dyspnea score,Maximum 10 points,Minimum 0,The higher the score, the harder it is to breathe
Time frame: Day 28
arterial partial pressure of oxygen,Partial pressure of oxygen in arterial blood,normal range is 80~100.
Time frame: Day 28
arterial partial pressure of oxygen divided by the oxygen concentration,Normal is greater than 400.
Time frame: Day 28
The distance the diaphragm drops during inhalation,normal is 1.4cm.
Time frame: Day 28
The rate at which the diaphragm contracts during inhalation,normal is 1.3cm/s.
Time frame: Day 28
The thickness of the diaphragm during inhalation,The thickness of diaphragm at the end of expiratory is about 0.25cm.
Time frame: Day 28
The thickness of the diaphragm during exhalation,The thickness of diaphragm at the end of expiratory is about 0.15cm.
Time frame: Day 28
Rate of diaphragmatic thickness change during breathing,Diaphragmatic dysfunction is considered less than 20%.
Time frame: 3 month
icu length of stay
Time frame: Month 3
Hospitalization time,length of stay in hospital.
Time frame: Day 28
The time it takes to get out of bed for the first time
Time frame: Day 28
Use of non-invasive ventilator,Whether to use non-invasive ventilator within 28 days.
Time frame: Day 28
Intubation,Whether endotracheal intubation was performed for invasive mechanical ventilation within 28 days
Time frame: Day 28
mortality
Time frame: Day 28
The incidence of new complications(pressure sores、thrombus、aspiration).
Contact information is provided by the study sponsor or research team.
Chinese PLA General Hospital
Other
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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