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Active, Not Recruiting

NCT Number: NCT06981507

Evaluation of the Effect of MARPE on Speech

This study investigates the effects of Miniscrew-Assisted Rapid Palatal Expansion (MARPE) on speech characteristics in adolescent and young adult patients.

While MARPE is a widely used orthodontic procedure for treating maxillary transverse deficiency, its potential impact on speech production has not been thoroughly evaluated. The aim of this study is to assess whether MARPE treatment causes any temporary or long-term changes in speech patterns using acoustic and perceptual analysis methods.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Age range

15 year–18 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Necmettin Erbakan University, Faculty of Dentistry

Konya, Meram, 42080, Turkey (Türkiye)

About this study

This prospective clinical study aims to evaluate how Miniscrew-Assisted Rapid Palatal Expansion (MARPE) affects speech in adolescents and young adults with skeletal maxillary transverse deficiency.

Speech production relies on precise palatal anatomy and oral resonance. Since MARPE modifies the palatal structure through skeletal expansion, it may influence articulation and acoustic properties of speech. Despite its increasing use in orthodontics, the potential speech-related side effects of MARPE remain largely unexplored.

Participants aged 13-25 will undergo MARPE treatment as part of their standard orthodontic care. Speech recordings will be taken at three time points: before expansion (baseline), immediately after the active expansion phase, and after the retention period. Acoustic analysis and standardized perceptual speech evaluations will be conducted to detect any phonetic, articulatory, or resonance-related changes.

The results will help clinicians better understand the functional implications of MARPE on speech and provide guidance for counseling patients before treatment.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with Class I malocclusion
  • Presence of maxillary transverse deficiency
  • Young adult patients aged 15 to 18 years
  • No history of systemic disease, cleft lip/palate, or speech disorders
  • No history of previous orthodontic treatment

Exclusion criteria

  • Patients with any systemic disease
  • Patients who smoke
  • Patients with poor oral hygiene
  • Patients with cooperation difficulties
  • Patients with mental retardation or cognitive impairment

Treatment and study plan

MARPE (Miniscrew-Assisted Rapid Palatal Expansion)

Device

MARPE (Miniscrew-Assisted Rapid Palatal Expansion) is an orthodontic expansion technique that uses a palatal expander anchored with miniscrews inserted into the palatal bone. The device applies lateral force to widen the maxilla skeletally in patients with transverse maxillary deficiency. In this study, all participants will receive MARPE treatment as part of their orthodontic management, and its potential effects on speech will be evaluated over time.

Primary outcomes

  1. Speech Changes After MARPE Treatment

    Time frame: Baseline and 1 month after expansion

Sponsors and collaborators

Lead sponsor

Konya Necmettin Erbakan Üniversitesi

Other

Registry information

Acronym: MARPE-Speech

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
May 20, 2025
Registry last updated
Sep 2, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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