Evaluation of the Effect of Laser Therapy on Lateral Pterygoid Muscle in Patients With Wilke's Stage I and II Temporomandibular Disorders (TMD): Case Series Study

The purpose of this study will be to evaluate the effect of laser therapy on lateral pterygoid muscle in patients with Wilke's stage I and II temporomandibular disorders (TMD).

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Key information

Conditions

LASER Craniomandibular Disorders Jaw Diseases Joint Diseases Lateral Pterygoid Muscle Mandibular Diseases Muscular Diseases Musculoskeletal Diseases Stomatognathic Diseases Temporomandibular Joint Disorders

Age range

16 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients age between 16-50 years with no sex predilection.
Patients who will be free from any systemic diseases that affect temporomandibular joint.
Patients who will be diagnosed with wilk's stage I and II temporomandibular disorders (TMD).
Patients who will be ready to give informed consent.

Exclusion criteria

Patients with previous temporo-mandibular surgeries.
Patients with previous facial fracture.
Patients who will be under another type of treatment for TMD (e.g., occlusal splints, pharmacological drugs, or head and neck surgery).
Patients who will not attend the proposed treatment sessions or follow-up visits.

Treatment and study plan

laser therapy in TMD

Procedure

In this study patients will receive the Low-level laser therapy with a 635 nm wavelength diode laser (Lasotronix, Diode Laser DiodeLX model SMART M; Zytnia, Piaseczno, Poland) with 200 mW in a continuous mode, using a handpiece with a cylindrical applicator with a diameter of 8 mm in contact mode extra-orally, fiber-optic applicator with a diameter of 8 mm in contact mode intraorally, with a power density of 400 mW/cm2, delivering 10-12 J/cm2 on each application point, over a period of 20 sec.

There are two methods for examination of lateral pterygoid muscle: digital palpation and functional manipulation.

For digital palpation of lateral pterygoid muscle, we place our index finger or tip of our little finger in the vestibular area adjacent to the maxillary third molar.

Functional manipulation of the inferior head of lateral pterygoid muscle: It is best accomplished by having the patient make a protrusive movement against resistance to contract it since this muscle is the primary pro

Primary outcomes

Pain: will be obtained by Visual analogue scale (VAS).

Time frame: pain will be measured : 1.day1 before the start of laser therapy, 2.week 1 3. week2 4.week 3 5. week 4 6.one month later 7. 3 months later.

Pain: will be obtained by Visual analogue scale (VAS).

Secondary outcomes

Mouth opening, lateral protrusive movement: will be obtained by a caliper.

Time frame: Mouth opening, lateral protrusive movement will be measured : 1.day1 before the start of laser therapy, 2.week 1 3. week2 4.week 3 5. week 4 6.one month later 7. 3 months later.

Mouth opening, lateral protrusive movement: will be obtained by a caliper.

Other outcomes

Clicking: will be obtained by Yes or No.

Time frame: Clicking will be measured : 1.day1 before the start of laser therapy, 2.week 1 3. week2 4.week 3 5. week 4 6.one month later 7.after 3 months.

Clicking: will be obtained by Yes or No.
Clicking: will be obtained by Yes or No.

Time frame: Clicking will be measured : 1.day1 before the start of laser therapy, 2.week 1 3. week2 4.week 3 5. week 4 6.one month later 7. 3 months later.

Clicking: will be obtained by Yes or No.

Study contacts

Contact information is provided by the study sponsor or research team.

aliaa ibrahim fathy khalifa, B.D.S 2019

CONTACT

[email protected]

01068111549

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Important dates

Study start: 2025
Primary completion: 2026
Study completion: 2026
First posted: May 31, 2025
Registry last updated: Jun 13, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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