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Completed

NCT Number: NCT01549249

Evaluation of the Cone Outer Segment Tips Line After Epiretinal Membrane Surgery

The recovery of the cone outer segment tips (COST) line after epiretinal membrane (ERM) surgery using spectral-domain optical coherence tomography (SD-OCT) was assessed.

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Key information

Conditions

Epiretinal Membrane Eye Diseases Retinal Diseases

Age range

40 year–90 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Kyorin Eye Center

Mitaka, Tokyo, 181-8611, Japan

About this study

Epiretinal membrane (ERM) may cause decreased central vision or metamorphopsia. Pars plana vitrectomy with membrane peeling has become the standard treatment for epiretinal membrane. However, visual recovery or symptomatic relief is not always satisfactory in all eyes despite successful membrane removal. Spectral domain optical coherence tomography (SD-OCT) is a non-invasive imaging device for various vitreoretinal diseases. Cone outer segment tips (COST) line is a line observed between IS/OS line and RPE in SD-OCT. The investigators examined the correlation of visual acuity and the recovery of photoreceptor layer after ERM surgery, taking COST line into account as a new parameter

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients who received epiretinal membrane surgery between June, 2008, and November, 2010, at Kyorin Eye Center.
  • Only eyes with postoperative follow-up period more than 6 months were included.

Exclusion criteria

  • Eyes with secondary epiretinal membrane (previous history of uveitis, intraocular surgery, pre-operatively noted retinal breaks, etc.) were excluded.

Treatment and study plan

optical coherence tomography

Device

spectral-domain optical coherence tomography

Other names: vitreous surgery

Primary outcomes

  1. best-corrected visual acuity

    Time frame: one year

Secondary outcomes

  1. Integrity and defect length of the photoreceptor layer detected by spectral-domain optical coherence tomography

    Time frame: one year

Sponsors and collaborators

Lead sponsor

Kyorin University

Other

Registry information

Important dates

Study start
2008
Primary completion
2010
Study completion
2011
First posted
Mar 9, 2012
Registry last updated
Nov 14, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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