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Completed

NCT Number: NCT05215444

Evaluation of Some Prognostic Factors in Acute Aluminum Phosphide Intoxicated Cases

study of some laboratory and clinical findings which may show the severity of aluminium phosphide toxicity and the need of the cases to be admitted to ICU

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Key information

Conditions

Aluminum Phosphide Poisoning

Age range

15 year–45 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Faculty of Medicine Zagazig University

Zagazig, Sharqia Province, 44511, Egypt

About this study

aluminium phosphide poisoning is a major cause of death in intoxicated and suicidal cases since there is no antidote and there is no specific investigation for it so there is a need for further study to identify the cause of death and the most specific investigation in the case of AlP toxicity

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • History of exposure or intake of Aluminum phosphide.
  • Clinical picture of Acute Aluminum phosphide poisoning including severe vomiting, hypotension, abdominal pain, cardio-pulmonary distress.
  • Cases of the age of 15 to 45 years old

Exclusion criteria

  • 1. Cases with an unclear history. 2. History of co-morbidities or systemic diseases because of the possibility of misleading laboratory results.
  • History of co-ingestion of drugs or another poison.

Treatment and study plan

some prognostic factors

Diagnostic Test

cortisol level, renin, troponin I, MDA ,catalase, super oxide dismutase, liver functions, kidney functions, arterial blood gases, sodium level, potassium level. white blood cells count

Primary outcomes

  1. prognosis

    Time frame: the first 24 post poisoning

    predict the mortality of intoxicated AlP cases

Sponsors and collaborators

Lead sponsor

Zagazig University

Other Gov

Registry information

Important dates

Study start
2021
Primary completion
2021
Study completion
2021
First posted
Jan 31, 2022
Registry last updated
Jan 26, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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