Evaluation of Sleep Mode Within the Respironics SimplyGo Portable Oxygen Concentrator

All participants will undergo a single night polysomnography testing in a sleep lab while they're oxygen saturation (SpO2) is monitored. The study has a cross-over design, in which participants will receive their oxygen prescription in two different modes at different times during the night. The assignment (sleep vs. continuous mode) to which participants will initiate the night will be randomized, and all participants will utilize each of the two modes during the study. The hypothesis of this study is that there will not be a significant difference in SpO2 for participants while they use the SimplyGo Portable Oxygen Concentrator, set in 'Sleep Mode', or pulsed oxygen flow, as compared to their SpO2 while on continuous flow oxygen during sleep during the course of the one night sleep study.

Inclusion criteria

• Males and Females, ages 21-80
• Current prescription for supplemental oxygen at night; Can be pulsed dose or continuous
• Willing and able to provide informed consent

Exclusion criteria

• Medically unstable participants per discretion of the principal investigator
• Diagnosis of sleep apnea, per chart review, self report or rated high risk based on the Berlin Questionnaire
• Participants unable or unwilling to spend one night in a sleep lab
• Nocturnal oxygen requirements > 5 liters per minute
• Currently employed by a manufacturer of respiratory products or family member employed by a manufacturer of respiratory products
• Employee or family member that is affiliated with Philips