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NCT Number: NCT03780218

Evaluation of Pulmonary Function in Burn Injury

This study evaluates the pulmonary function, respiratory muscle strength and peripheral muscle strength in patients with burn injury on the week that they will be discharge from the hospital. Healthy subjects will be evaluated for pulmonary function, respiratory muscle strength and peripheral muscle strength.

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Key information

Conditions

Burns Wounds and Injuries

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Ozden Ozkal

Ankara, 06100, Turkey (Türkiye)

About this study

Burn injures have adverse effect on the respiratory system.In addition to burn injury prolonged hospitalization may increase the ratio of respiratory complications. But, there are no information in the literature about pulmonary function, respiratory muscle strength and peripheral muscle strength in patients with burn injury. Especially, when the patients are discharged from the hospital, it is not known whether the patients are at the same level in terms of pulmonary functions respiratory muscle strength and peripheral muscle strength with healthy individuals. This study will assess pulmonary functions respiratory muscle strength and peripheral muscle strength in patients with burn injury compared to healthy subjects.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Having a burn injury
  • Treatment by an inpatient
  • able and willing to complete the informed consent process.
  • Control group consists of healthy adults with the similar demographic characteristics as experimental group

Exclusion criteria

  • having a pulmonary system disease
  • having a cardiac system disease
  • to do regular sports for the last three months

Treatment and study plan

Respiratory function

Other

Respiratory function test evaluates the participants' pulmonary function and respiratory muscle strength

Primary outcomes

  1. Forced Vital Capacity

    Time frame: 15 minutes

    is the total amount of air exhaled during the test. After three trial, the best forced vital capacity value is the outcome

  2. Forced Expiratory Volume in 1 Second

    Time frame: 15 minutes

    Forced Expiratory Volume in 1 Second is the volume exhaled during the first second of a forced expiratory maneuver started from the level of total lung capacity. After three trial, the best FVC value is the outcome.

  3. Forced Expiratory Volume in 1 Second / Forced Vital Capacity

    Time frame: 15 minutes

    The ratio of Forced Expiratory Volume in 1 Second / Forced Vital Capacity. This formule is calculated by measuring device. After three trial, the best value is the outcome.

  4. Maximal Inspiratory Pressure

    Time frame: 15 minutes

    is a measure of the strength of inspiratory muscles, primarily the diaphragm. It is obtained by having the patient inhale as strongly as possible against a mouthpiece. After three trial, the best value is the outcome.

  5. Maximal Expiratory Pressure

    Time frame: 15 minutes

    a measure of the strength of respiratory muscles, obtained by having the patient exhale as strongly as possible against a mouthpiece. After three trial, the best value is the outcome.

Secondary outcomes

  1. Peak Expiratory Flow

    Time frame: 15 minutes

    Peak Expiratory Flow is a person's maximum speed of expiration, as measured with a peak flow meter, a small, hand-held device used to monitor a person's ability to breathe out air. After three trial, the best value is the outcome.

  2. forced expiratory flow

    Time frame: 15 minutes

    Forced expiratory flow is the flow (or speed) of air coming out of the lung during the middle portion of a forced expiration.

  3. Peripheral strength

    Time frame: 15 minutes

    Peripheral (Grip) strength is a measure of muscular strength or the maximum force/tension generated by one's forearm muscles

  4. Pain severity

    Time frame: 15 minutes

    Pain severity was assessed by visual analogue scale. This scale score range from "no pain=0 point " to "worst imaginable pain=10 points" for intensity. Maximum point means worst pain severity.

  5. Functional Exercise Capacity

    Time frame: 10 minutes

    It was evaluated by six minutes walk test.The 6-min walk test is a submaximal exercise test that entails measurement of distance walked over a span of 6 minutes. The distance will be recorded. The higher distance is indicated better exercise capacity.

Sponsors and collaborators

Lead sponsor

Hacettepe University

Other

Collaborators

  • Ankara City Hospital Bilkent

Registry information

Official study title

Evaluation of Pulmonary Function and Respiratory Muscle Strength in Patients With Burn Injury.

Important dates

Study start
2019
Primary completion
2019
Study completion
2019
First posted
Dec 19, 2018
Registry last updated
Nov 1, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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