Aventure AB
Lund, Sweden
NCT Number: NCT03722641
The objective of this study is to investigate the effect on postprandial glycaemia in a healthy population after intake of milk and oat based products.
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Notify Me20 year–40 year
All sexes
Interventional
Not applicable
Lund, Sweden
Postprandial glycaemia, insulinaemia and GLP-1 will be measured after intake of test meals with equal amount of carbohydrates (adjusted using bread) and equal amount of total water.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Commercially available white wheat bread
Developed reference product based on milk
Developed product based on full fat milk with addition of oat
Developed product based on skim milk with addition of oat giving a high fiber content to the product
Developed product based on skim milk with addition of oat giving a lower fiber content to the product
Time frame: 0-120 min after consumption
Primary outcome is the difference in the two-hour incremental area under the curve (iAUC (0 - 120 min)) for capillary blood glucose between product 1-4 and the bread reference.
Time frame: 0-120 min
The difference in the two-hour iAUC (0 - 120 min) for intravenous blood glucose between product 1-4 and the bread reference.
Time frame: 0-180 min
The difference in the three-hour Cmax (0 - 180 min) of capillary blood glucose between product 1-4 and the bread reference.
Time frame: 0-180 min
The difference in the three-hour Cmax (0 - 180 min) of intravenous blood glucose between product 1-4 and the bread reference.
Time frame: 0-180 min
The difference in the three-hour iAUC (0 - 180 min) of capillary blood glucose between product 1-4 and the bread reference.
Time frame: 0-180 min
The difference in the three-hour iAUC (0 - 180 min) of intravenous blood glucose between product 1-4 and the bread reference.
Time frame: 0-60 min
The difference in the one-hour iAUC (0 - 60 min) of capillary blood glucose between product 1-4 and the bread reference.
Time frame: 0-60 min
The difference in the one-hour iAUC (0 - 60 min) of intravenous blood glucose between product 1-4 and the bread reference.
Time frame: 0-180 min
The difference in the Tmax (the time to maximum concentration) of capillary blood glucose between product 1-4 and the bread reference.
Time frame: 0-180 min
The difference in the Tmax of intravenous blood glucose between product 1-4 and the bread reference.
Time frame: 0-180 min
The difference in the three-hour iAUC (0 - 180 min) of intravenous blood insulin between product 1-4 and the bread reference.
Time frame: 0-120 min
The difference in the two-hour iAUC (0 - 120 min) of intravenous blood insulin between product 1-4 and the bread reference.
Time frame: 0-60 min
The difference in the one-hour iAUC (0 - 60 min) of intravenous blood insulin between product 1-4 and the bread reference.
Time frame: 0-180 min
The difference in the three-hour Cmax (0 - 180 min) of intravenous blood insulin between product 1-4 and the bread reference.
Time frame: 0-180 min
The difference in the Tmax of intravenous blood insulin between product 1-4 and the bread reference.
Time frame: 0-60 min
The difference in the one-hour iAUC (0 - 60 min) of intravenous blood GLP-1 between product 1-4 and the bread reference.
Time frame: 0-60 min
The difference in the one-hour iAUC (0 - 60 min) of intravenous blood GLP-1 between products 2-4 and product 1.
Time frame: 0-60 min
The difference in the one-hour Cmax (0 - 60 min) of intravenous blood GLP-1 between product 1-4 and the bread reference.
Time frame: 0-60 min
The difference in the one-hour Cmax (0 - 60 min) of intravenous blood GLP-1 between products 2-4 and product 1.
Aventure AB
Industry
A Randomized, Single-blind, Crossover Study to Evaluate Postprandial Glycaemia in a Healthy Population After Intake of Milk and Oat Based Products
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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