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NCT Number: NCT07287683

Evaluation of Postoperative Pain in Cases Undergoing Cataract Surgery Under Topical Versus General Anesthesia

Comparison between cataract surgery under local versus general anesthesia regarding postoperative pain, complications and patient satisfaction and need for rescue analgesic intake after surgery The results will be followed up at 24 hrs, 1 week and after one and half month following the surgery.

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This study is active but is not currently recruiting participants.

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Key information

Conditions

Topical Anaesthesia Cataract Eye Diseases General Anesthetic Drug Adverse Reaction Lens Diseases

Age range

20 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1 / Phase 2

Primary location

Faculty of Medicine

Alexandria, Egypt

About this study

This prospective randomized controlled study will be carried out on 50 adult patients. Written informed consent will be taken from all prospective cases.

The cases will be selected having (ASA1), (ASA II) or (ASA III) physical status in the age range between 20 and 70 years old with cataract eye disease.

This study will be performed in Alexandria Main University Hospital, Egypt. Patients will be followed up at 24 hours, 1 week, and 6 weeks after surgery.

The following measurements will be recorded

  • Pain will be assessed prior to surgery and after surgery using VAS score at 24 hours, 1 week, and 6 weeks after surgery.
  • Need for analgesic intake after surgery will be assessed for the first 48 hours
  • Complications after surgery as irritation, infection ,and foreign body sensation were assessed
  • Patient satisfaction will be assessed.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with unilateral cataract planned for surgery under topical or general anesthesia

Exclusion criteria

  • patients under 20 or over 70 years old Eye infection Patient refusal

Treatment and study plan

Topical Anaesthesia group

Drug

This group of patients will only receive topical anaesthesia for Cataract surgery

Other names: Topical group

General Anaesthesia group

Drug

General Anaesthesia will be given to this group undergoing cataract surgery

Primary outcomes

  1. Post operative pain

    Time frame: At 24 hours, one week and 6 weeks following surgery

    Postoperative pain will be assessed using the Visual Analogue Scale (VAS), ranging from 0 (no pain) to 10 (worst pain imaginable).

Secondary outcomes

  1. 1-complications after surgery 2-Patient satisfaction will be measured using the IOWA Satisfaction with Anaesthesia Scale (ISAS), which ranges from 6 (very satisfied) to 3 or less (dissatisfied).

    Time frame: Up to 6 weeks

    Complications including hypotension, nausea and allergic reaction will be assessed after surgery and 24 hours later. satisfaction assessment will evaluate patient safety, pain control, comfort, nausea, interaction with the surgical team, willingness to repeat the anaesthetic, and relaxation during and after surgery. Patient satisfaction will be recorded at one week and six weeks postoperatively.

Sponsors and collaborators

Lead sponsor

Alexandria University

Other

Registry information

Official study title

Evaluation of Postoperative Pain in Cases Undergoing Cataract Surgery Under Topical Anaesthetic Versus General Anaesthesia

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Dec 17, 2025
Registry last updated
Dec 17, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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