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Completed

NCT Number: NCT03859778

Evaluation of Pharmacy Students' Perception of Opioid / Opiate Dependence

The pharmacist in his professional activity may have to manage opioid dependent patients. This professional activity will result in the provision of opioid substitution treatment (OST), single-use syringes, harm reduction kits and a prevention advice for the reduction of toxicity and infection risks.

Since the 1990s, the consumption of OST has been steadily increasing. According to the OFDT (French Observatory of Drugs and Drug Addiction), the number of patients under OST is about 150 000 patients. Since high-dose buprenorphine is prescribed for approximately two-thirds of patients, it remains the most frequently prescribed OST in France.

Recently, a French association assisting drug users (ASUD - Auto-support des usagers de drogues) performed a study in Paris (20/07/2018 - 25/08/2018) to assess the delivery of opioid replacement therapies by community pharmacists. In this study, 71% of pharmacists refused to deliver opioid replacement therapies. The main reasons reported were security (56%) and activity saturation, meaning that pharmacists considered that they had too many patients using opioid drugs. In France, the refusal of a pharmacist to deliver drugs is a punishable offence. According to the Code of ethics of pharmacists, pharmacists must respect life and people without discrimination. Pharmacists have a low perception of patients suffering from opioid addiction. Another study performed by ASUD in 93 community pharmacies, showed that pharmacists used the term "toxicomaniacs" instead of "drug users". Most pharmacists had had a bad experience with drugs users, with physical and verbal aggressions. The conclusions of this study showed that pharmacists lacked knowledge of drug users and drug use. Pharmacists knew about harm reduction kits for opioid users (containing sterile syringes, needles, water, antiseptics, etc.) and had already opened them, but very few knew how to use them. More worryingly, some pharmacists did not understand the harm reduction strategies available It thus appears that community pharmacists have a difficult relationship with opioid-dependent patients, even though these pharmacists have received education in the management of addictions during their studies. Indeed, it can consider that these courses should help to better understand the addictive disease both in its nosological / semiological and therapeutic components. Thus, it would be interesting to evaluate the impact of addiction education on pharmacists' perception of opioid dependence. In this perspective, it would be interesting to focus on pharmacy students.

The objective of this study will be to evaluate the perception by pharmacy students of opioid dependent patients. Investigator would like to know if pharmacy students consider opioid addiction to be an illness and whether having taken education on drug use and addictions changes this perception.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Chu Clermont-Ferrand

Clermont-Ferrand, 63003, France

About this study

This observational and cross-sectional study will be conducted as a survey using the REDCap software and the response to this survey will be done online, in real time, with an automatic, secure and centralized data collection (CHU Clermont-Ferrand).

French pharmacy students will be contacted by email thanks to the student associations and scolarity departments. Answer to the survey will be done online.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • French pharmacy students

Exclusion criteria

  • Age <18 years
  • Other health students
  • Graduated pharmacist
  • First year pharmacy student

Treatment and study plan

Survey

Other

French pharmacy students will be contacted by email thanks to the student associations and scolarity departments. Answer to the survey will be done online

Primary outcomes

  1. Perception of opioid / opiate dependence as a disease

    Time frame: At day 1

    visual analogic scale: -10 (it is not a disease), 0 (neutral) and +10(it is a disease)

Secondary outcomes

  1. Proportion of courses on drug addiction during pharmacy studies

    Time frame: At day 1

    yes/no (percentage)

  2. Study year of courses on drug addiction during pharmacy studies

    Time frame: At day 1

    2nd, 3rd, 4th, 5th and/or 6th year of study in pharmacy

  3. Perception of the pharmacist's missions on the dispensing of opioid substitution treatments (buprenorphine and methadone) and harm reduction kit / single use syringe

    Time frame: At day 1

    visual analogic scale: -10 (it's not normal), 0 (neutral) and +10 (it's normal)

  4. Perception of the efficacy of opioid substitution treatments (buprenorphine and methadone)

    Time frame: At day 1

    visual analogic scale: -10 (it is not effective), 0 (neutral) and +10 (it is effective)

  5. Proportion of realization of internships or temporary employment in pharmacy

    Time frame: At day 1

    yes / no (percentage)

  6. Proportion of delivery of opioid substitution treatments (buprenorphine and methadone)

    Time frame: At day 1

    yes / no (percentage)

  7. Proportion of tobacco (cigarettes) use

    Time frame: At day 1

    yes / no (percentage)

  8. Proportion of electronic cigarettes use

    Time frame: At day 1

    yes / no (percentage)

  9. Proportion of alcohol use

    Time frame: At day 1

    yes / no (percentage)

  10. Proportion of alcohol use (>10 alcohol units per week)

    Time frame: At day 1

    yes / no (percentage)

  11. Proportion of cannabis use

    Time frame: At day 1

    yes / no (percentage)

  12. Frequency of cannabis use (for users)

    Time frame: At day 1

    Daily, weekly, monthly, occasional or experimentation

  13. Proportion of personal experience with a relative having or having had a problem of drug use

    Time frame: At day 1

    yes / no (percentage)

  14. Academic year in pharmacy at the time of the answer

    Time frame: At day 1

    2nd / 3rd / 4th / 5th / 6th year of study in pharmacy

  15. Estimation of attendance to courses

    Time frame: At day 1

    Visual analogic scale: 0 (no attendance) - 100 (full attendance)

  16. Estimation of annual average mark during the past university year

    Time frame: At day 1

    <10, 10-12, 12-14, 14-16 and >16/20

  17. Demographic information

    Time frame: At day 1

    age and sex

Sponsors and collaborators

Lead sponsor

University Hospital, Clermont-Ferrand

Other

Collaborators

  • UFR Pharmacie (Clermont-Ferrand)

Registry information

Official study title

Evaluation of Pharmacy Students' Perception of Opioid / Opiate Dependence: Cross-sectional National Study

Acronym: STUD_TOX

Important dates

Study start
2019
Primary completion
2019
Study completion
2019
First posted
Mar 1, 2019
Registry last updated
May 24, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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