Evaluation of PET/MRI in Patients With Pancreatic Adenocarcinoma

Patients will receive a PET/MRI scan within 6 weeks of their standard of care imaging. There is no maximum number of scans for research. The number of scans depends on each patient's treatment plan.

Inclusion criteria

• Presence of suspicious lesion of the pancreas consistent with pancreatic adenocarcinoma. Cytological confirmation is not required.
• Patients preparing to receive therapy for pancreas cancer, including patients enrolled in NCT01413022
• Patient must be 18 years or older
• Patient must have a life expectancy of more than 6 months and performance status of 2 or less
• Patient must be able to understand and willing to sign an approved written informed consent document
• Women of childbearing potential and men must agree to use adequate contraception prior to study entry and for the length of the study
• Patients enrolled in the Clinical trials.gov# NCT01413022 trial must meet both studies eligibility criteria.

Exclusion criteria

• Patient must not have had prior resection for pancreatic adenocarcinoma.
• Patient must not have a history of other malignancy less than or equal to 5 years previous with the exception of basal cell or squamous cell carcinoma of the skin which were treated with local resection only or carcinoma in situ of the cervix
• Patient must not be unable to receive a PET-MRI scan due to renal function, allergy or other problem with receiving or tolerating an MRI scan, etc. All patients will fill out a standard MRI screening form.
• Patients must not have a blood glucose of greater than or equal to 200mg/dL at the time of PET-MRI or if a patient is diabetic and glucose is not controlled. At the discretion of the PI and the authorized user and with their approval prior to 2-[18]fluoro-2-deoxy-D-glucose (FDG) injection, patients with blood glucose ≥ 200 mg/dL may participate in the study.
• Patient must not be pregnant and/or breast feeding