Evaluation of Peripheral Microcirculation Hemodynamics Following Various Changes Based on Noninvasive Thermography

This study includes a single session per subject. Microvascular and systemic variables will be monitored in response to a number of non-invasive interventions/device that are approved for clinical use and known to elicit microvascular responses. These interventions are applied consecutively, include breathing at different rates, low power visible light in the red-to-near-infrared range, increase in local temperature, and changes in the arm position.

Inclusion criteria

• Healthy males and females, between 23 and 45 years of age.
• Willing to sign informed consent

Exclusion criteria

• Currently smoking
• Any abnormal skin condition in the area of light irradiation.
• Pregnant having given birth less than 3 months ago, and/or breastfeeding.
• Having a history of diseases stimulated by heat, such as recurrent Herpes Simplex in the treated area, unless treatment is conducted following a prophylactic regimen.
• Having any illness that might affect the vasculature, such as diabetes (type I or II)
• Suffering from significant concurrent illness, such as cardiac disorders or pertinent neurological disorders.
• As per the Investigator's discretion, any physical or mental condition which might make it unsafe for the subject to participate in this study.