Completed

NCT Number: NCT02779166

Evaluation of Perioperative Celecoxib for Hip Arthroscopy

Celecoxib is commonly used for perioperative pain control for certain orthopaedic procedures. It has been shown to be successful in assisting in pain control for knee arthroscopy. It has not previously been studied in hip arthroscopy. This is a double blinded randomized controlled trial to determine the efficacy of celecoxib in perioperative pain control for hip arthroscopy.

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Key information

Conditions

Hip Labral Tears

Age range

18 year–89 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

This study examines the efficacy of perioperative dose of celecoxib in pain management after hip arthroscopy. Perioperative administration of celecoxib has been shown to improve pain control after knee arthroscopy, but this has not yet been studied in the hip. In this study, patients are randomized to receive either 400mg celecoxib or placebo 1 hour prior to undergoing hip arthroscopy surgery. Postoperatively, patients are monitored for pain on the VAS scale, narcotic use, and meeting discharge criteria. The study will enroll 100 patients. Patients are approached for informed consent on the day of surgery. Pain scores, narcotic use, and time to discharge in the celecoxib group are compared to the placebo group.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

All patients who are undergoing a hip arthroscopy procedure at Northwestern Memorial Hospital with Dr. Michael Terry.

Exclusion criteria

Pregnant women and any patient under the age of 18 years.

Treatment and study plan

Celecoxib

Drug

Received 400mg celecoxib prior to surgery

Placebo

Drug

Primary outcomes

Visual Analog Score for Pain (VAS) in the Immediate Post Operative Period

Time frame: Pre operative on day of surgery, immediately following OR close, 1 hr post operatively, 2 hrs post operatively

The pain VAS is a uni dimensional measure of pain intensity. It is a continuous scale comprised of a 0-10 pain rating. A score of 0 indicates no pain while a score of 10 would indicate extreme pain.
Total Narcotic Consumption in the Post Anesthesia Care Unit (PACU)

Time frame: duration of PACU stay,immediate post op period up to a maximum of 4 hours postoperatively

Monitored consumption of narcotic medications following surgery, measured in morphine equivalents
Time to Discharge Following Surgery

Time frame: time from OR to discharge, up to a maximum of 6 hours postoperatively

Total time to discharge from OR close following surgery, measured in minutes

Sponsors and collaborators

Lead sponsor

Northwestern University

Other

Registry information

Acronym: Celecoxib

Important dates

Study start: 2012
Primary completion: 2016
Study completion: 2016
First posted: May 20, 2016
Registry last updated: Sep 23, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.