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OpenTrials
Completed

NCT Number: NCT04011839

Evaluation of Perineural Catheterization Practices in Postoperative Orthopedic Surgery

Continuous peripheral nerve blocks are considered as the gold standard for postoperative analgesia in orthopaedic surgery (shoulder, knee, foot). These techniques are also used in chronic pain.

The main disadvantage of these techniques is that they can drive a more or less deep motor block that slows down the rehabilitation process. This disadvantage could be prevented (or minimized) by adapting the protocol for administering local anesthetics or by changing molecules (levobupivacaine 0.625 mg/ml instead of ropivacaine 2 mg/ml). There is no literature comparing the effectiveness of the sensory block and its impact on the motor block according to the administration protocol and/or the type of local anesthetics.

The main judgement criterion of such a study could be a composite criterion crossing the quality of the sensory block and the depth of the motor blockades, the ideal being to have a perfect sensory block without any motor block.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

CHU de NIMES

Nîmes, 30029, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • >18 years old
  • ASA score 1 to 4
  • Scheduled orthopaedic surgery
  • consent to participate

Exclusion criteria

  • Pregnant, parturient, or breastfeeding woman
  • Emergency situation
  • Contraindications to local anaesthesia
  • Patient refusal

Treatment and study plan

Levobupivacaïne

Drug

Use of Levobupivacaïne instead ropivacaïne

Primary outcomes

  1. Comparison between sensory Block Quality and motor Block deep

    Time frame: Day1 to Day 3

    Composite score between 0 to 2 for Sensory Block and 0 to 2 for motor Block

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire de Nīmes

Other

Registry information

Acronym: Cathepos

Important dates

Study start
2021
Primary completion
2022
Study completion
2022
First posted
Jul 9, 2019
Registry last updated
May 30, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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