Completed
NCT Number: NCT01803217
Evaluation of Pacemaker Algorithms to Avoid Unnecessary Right Ventricular Pacing
Unnecessary right ventricular pacing has been shown to be detrimental in recipients of implantable pacemaker or defibrillators.
The ADVANTAGE study evaluates the efficacy of two pacemaker based algorithms (atrioventricular hysteresis function versus mode switch to atrial pacing) to reduce right ventricular pacing.
Completed
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Notify MeKey information
Age range
18 year and older
Sex eligibility
All sexes
Study type
Interventional
Phase
Not applicable
Primary location
Klinikum Bamberg, Bamberg, Bavaria, Germany
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About this study
Comparison of the effect of an atrioventricular hysteresis function with a mode switch to atrial pacing on the right ventricular pacing percentage in a multi-centre, prospective, randomized, single blinded, cross-over study.
Who can participate
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Indication for the implantation of a dual-chamber pacemaker
Exclusion criteria
Persistent or permanent atrial tachyarrhythmias atrioventricular block 2nd or 3rd degree indication or the implantation of an defibrillator
Treatment and study plan
Primary outcomes
-
Right ventricular pacing percentage
Time frame: 3 months
Secondary outcomes
-
BNP levels
Time frame: 3 months
Other outcomes
-
Occurrence of atrial tachyarrhythmias
Time frame: 3 months
Sponsors and collaborators
Lead sponsor
Deutsches Herzzentrum Muenchen
Other
Collaborators
- Klinikum Bamberg
- Krankenhaus Peißenberg
- Medtronic
Registry information
Official study title
AV-Hysteresis Versus Mode Switch to AAI (MVP) for the Avoidance of Unnecessary Right Ventricular Pacing
Acronym: ADVANTAGE
Important dates
- Study start
- 2007
- Primary completion
- 2011
- Study completion
- 2016
- First posted
- Mar 4, 2013
- Registry last updated
- Apr 10, 2017
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.