Evaluation of Optimal Dosing Conditions for GLP-1 Analogue NNC0113-0987 When Administered Orally in Healthy Male Subjects

Inclusion criteria

• Male aged 18 between 55 years (both inclusive) at the time of signing informed consent
• Good general health based on medical history, physical examination, and results of vital signs, electrocardiogram and laboratory safety tests performed during the screening visit, as judged by the investigator
• Body mass index (BMI) between 18.5 and 29.9 kg/m^2 (both inclusive)

Exclusion criteria

• History of, or presence of, cancer, diabetes or any clinically significant cardiovascular,respiratory, metabolic, renal, hepatic, gastrointestinal, endocrinological, haematological, dermatological, venereal, neurological, psychiatric diseases or other major disorders, as judged by the investigator
• Blood pressure above 140 mmHg systolic and/or above 90 mmHg diastolic or pulse above 90 beats per minute at the screening visit
• Smoking more than 5 cigarettes or the equivalent per day (including use of nicotine substitute products)
• History of significant drug abuse, or a positive drug test at the screening visit
• Any blood draw in excess of 25 mL in the past month, or donation of blood or plasma in excess of 400 mL within the 3 months preceding the screening visit