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NCT Number: NCT06833775

Evaluation of Neoadjuvant Therapy Efficacy and Postoperative Pathological Indicators in Esophageal Cancer Using CT and Multimodal MRI

This study aims to predict the efficacy of different types of neoadjuvant therapy and related postoperative pathological indicators in patients with esophageal cancer based on imaging parameters from CT and multimodal MRI, as well as clinical indicators collected before and after neoadjuvant treatment.

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Key information

Conditions

Esophageal Cancer Digestive System Diseases Digestive System Neoplasms Esophageal Diseases Esophageal Neoplasms Gastrointestinal Diseases Gastrointestinal Neoplasms Head and Neck Neoplasms Neoadjuvant Therapy Neoplasms Neoplasms by Site

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Consecutive patients with histopathological diagnosis of esophageal cancer.
  • Patients underwent neoadjuvant therapy before radical surgery for esophageal cancer: neoadjuvant chemotherapy, neoadjuvant chemoradiotherapy, neoadjuvant chemotherapy plus immunotherapy, neoadjuvant chemoradiotherapy plus immunotherapy.
  • All patients underwent CT and multimodal MRI examinations before and after neoadjuvant therapy.
  • The preoperative clinical data and postoperative pathological data are complete.

Exclusion criteria

  • Patients with other primary malignant tumors or previous anti-tumor treatment.
  • CT and MRI images with poor quality.

Treatment and study plan

Primary outcomes

  1. CT and multimodal MRI in prediction of neoadjuvant therapy efficacy and postoperative pathological indicators in esophageal cancer

    Time frame: March 2025 - January 2030

    To evaluate the effectiveness of CT and multimodal MRI in determining the neoadjuvant therapy efficacy and postoperative pathological indicators in esophageal cancer.

Study contacts

Contact information is provided by the study sponsor or research team.

Jinrong Qu

CONTACT

[email protected]

(86) 0371-65587595

Sponsors and collaborators

Lead sponsor

Henan Cancer Hospital

Other Gov

Registry information

Important dates

Study start
2025
Primary completion
2030
Study completion
2030
First posted
Feb 19, 2025
Registry last updated
Feb 20, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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