Evaluation of Morphology Abnormal Cornea Stability With Corneal Biomechanical

To evaluate the corneal biomechanical properties of stable eyes with abnormal morphology, and introduce a biomechanical stable index to evaluate the stability of the eyes with abnormal morphology at the first diagnosis.

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Key information

Conditions

Keratoconus, Stable Corneal Diseases Eye Diseases Keratoconus

Sex eligibility

All sexes

Study type

Observational

Primary location

Tiajin Eye Hospital

Tianjin, Tianjin Municipality, China

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Best corrected visual acuity (BCVA) ≥ 20/20;
No other eye diseases except myopia and astigmatism;
The cornea was transparent, and there was no cloud or pannus;
No clinical manifestation of keratoconus（Corneal stromal thinning, Cone-shaped anterior protrusions, Fleischers ring, Vogts striae, Epithelial or subepithelial scarring） Exclusion Criteria:1) corneal disease;

ocular trauma; 3) Patients were required to stop wearing soft contact lenses for at least 2 weeks and rigid contact lenses for at least 4 weeks before examination; 4) Pregnant and lactating women;

Treatment and study plan

Pentacam and Corvis ST

Other

morphological and biomechanical parameters of corneal were obtain by Pentacam and Corvis ST

Primary outcomes

stable

Time frame: one year

No alterations in morphological(Pentacam parameters, BAD<0.42, TCT<10μm) and biomechanical(Corvis ST, parametersCBI<0.2, SPA1<10) parameters between the first and last follow-up.

Sponsors and collaborators

Lead sponsor

Tianjin Eye Hospital

Other

Registry information

Official study title

Prediction for Abnormal Topography Corneas Using New Biomechanical Parameter - Biomechanical Stable Index

Important dates

Study start: 2018
Primary completion: 2022
Study completion: 2022
First posted: Feb 28, 2023
Registry last updated: Oct 23, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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