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Completed

NCT Number: NCT02825121

Evaluation of Monitoring Neuromuscular Blockade the Flexor Hallucis Compared to the Adductor Pollicis

Current guidelines recommend monitoring of neuromuscular blockade at the adductor pollicis by stimulation of the ulnar nerve at the wrist.

However, in certain situations (laparoscopic surgery, cranial surgery or surgical comfort, arterial catheterization), it is impossible to access the patient's wrists, delaying monitoring, antagonizing the neuromuscular block, the emergence from anesthesia and patient extubation , leading in some cases to single injections lack of control of the reversal of the patient.

To overcome these technical difficulties, a group nerve / muscle looks interesting and often easily accessible to the anesthesiologist.

The stimulation of the posterior tibial nerve can observe a response to the flexor hallucis brevis muscle and allows quick access to monitoring the reversal before the end of the intervention.

The primary outcome was to compare the speed of recovery from neuromuscular block flexor hallux versus that of the adductor pollicis.

The secondary objective was to compare the speed of installation of deep neuromuscular block flexor hallucis versus that of the adductor pollicis.

This is a prospective, exploratory, uncontrolled, single-center for routine care.

Are included all aged patients over 18 years, ASA I or II, without guardianship, having no known allergy to Atracurium, without neuromyopathy known, emergency surgery or full stomach, predictable difficult intubation .

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Poitiers Universitary Hospital

Poitiers, 86021, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • over 18 years
  • Any elective surgery with single or multiple injection Atracurium for which hand and foot are accessible at the same time.
  • ASA I or II patients
  • free subject, without guardianship or subordination
  • No opposition given by the patient after information

Exclusion criteria

  • under 18 years
  • known neuromyopathy
  • Diabetics
  • Emergency surgery and a full stomach
  • predictable difficult intubation
  • Pregnant or breastfeeding women, women of childbearing age who do not have effective contraception

Treatment and study plan

Monitoring Neuromuscular Blockade the Flexor Hallucis

Device

Monitoring Neuromuscular Blockade adductor of the thumb.

Device

Primary outcomes

  1. Time of occurrence of a T4 / T1 ratio> 0.90 in the train of four flexor hallucis

    Time frame: 1 day

Sponsors and collaborators

Lead sponsor

Poitiers University Hospital

Other

Registry information

Acronym: CurHaTOF

Important dates

Study start
2016
Primary completion
2017
Study completion
2017
First posted
Jul 7, 2016
Registry last updated
Oct 5, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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