Evaluation of Low Energy Level Laser Biostimulation at Different Energy Densities in the Treatment of Temporomandibular Joint Irregularities: A Retrospective Study

This clinical study aimed to evaluate the effectiveness of low-level laser therapy in patients with temporomandibular disorders (TMD), specifically disc displacement with reduction and myalgia. The study compared laser therapy with a soft diet approach to determine whether laser treatment provides additional benefits in reducing pain and improving jaw function

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Key information

Conditions

Myalgia of Mastication Muscle

Age range

15 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Karadeniz Technical University

Trabzon, 61000, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Diagnosis of disc displacement with reduction (DDwR) and myalgia according to DC/TMD criteria Presence of temporomandibular joint pain and functional limitation Patients aged 18 years and older No previous temporomandibular joint (TMJ) treatment Absence of systemic diseases Willingness to participate and provide informed consent

Exclusion criteria

History of previous TMJ treatment (e.g., conservative or surgical treatment) Congenital or inflammatory joint disease Severe systemic diseases Edentulous patients Children and adolescents in the active growth period Acute trauma history involving the TMJ region Inability or unwillingness to complete follow-up visits

Treatment and study plan

Low Level Laser Therapy

Other

Participants received low-level laser therapy applied to the temporomandibular joint region in addition to soft diet recommendations. Treatment was performed in 9 sessions according to the predefined laser protocol. Participants followed a soft diet regimen without receiving laser therapy and served as the comparison group.

Dietary Supplement

Other

Participants in this group did not receive laser therapy and were instructed to follow a soft diet during the study period. This group served as the comparison group for evaluating treatment outcomes.

Primary outcomes

Change in temporomandibular pain intensity measured by the Visual Analog Scale (VAS) from baseline to the end of treatment and follow-up

Time frame: 6 month

Change in temporomandibular pain intensity was assessed using the Visual Analog Scale (VAS) from baseline to the end of treatment and follow-up. The Visual Analog Scale ranges from 0 to 10, where 0 indicates no pain and 10 indicates the worst pain imaginable. Higher scores represent greater pain severity.

Sponsors and collaborators

Lead sponsor

Karadeniz Technical University

Other

Registry information

Official study title

The Study Was Conducted by Retrospectively Analysing the Files of Patients Who Presented With Temporomandibular Joint Disorder (TMD) and Underwent LLEL Treatment. Patients Were Divided Into Myalgia, Disc Displacement With Reduction and Follow-up Groups. In Our Study, GaAl-As Diode Laser (EzLase 940, Biolase Technology, Inc. 4 Cromwell Irvine, USA) for Lowlevel Laser Treatment Was Applied for 1 Minute to Subgroup 1 (940 nm, 1. 5 W, 90 J, Continuous), Subgroup 2 (940 nm, 3 W, 180J, Continuous) and Subgroup 1 (940 nm, 1.5 W, 90J, Continuous) and Subgroup 2 (940 nm, 3 W, 180J, Continuous).

Important dates

Study start: 2022
Primary completion: 2024
Study completion: 2024
First posted: May 15, 2026
Registry last updated: May 15, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed