Skip to main content
OpenTrials
Completed

NCT Number: NCT01882582

Evaluation of Immune Signaling Networks in Healthy Human Volunteers

The purpose of this study is to better understand whether and to what extent the activity of immune cells in blood varies over time under normal conditions as assessed in healthy subjects. Results of this study will provide the foundation for helping us evaluate changes in immune cell activities in response to surgery and drugs used in anesthesia. The overall purpose of our research is to understand immune health in the context of anesthesia and surgery.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Normal Immune Cell Function

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Stanford University

Stanford, California, 94305, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 18-50
  • Good general health

Exclusion criteria

  • Recent cold or flu
  • Chronic use of medications affecting the immune system
  • Chronic illness
  • Smoking habit
  • History of drug abuse
  • Current recreational drug use

Treatment and study plan

Primary outcomes

  1. Numerical and functional changes of circulating immune cells over time in healthy individuals

    Time frame: Day 1, Day 2, Day 7, Day 28

    This is an exploratory study. Numerical and functional (phosphorylation of signaling molecules and transcription factors) behavior of all circulating immune cells will be captured. Blood specimens collected at referenced time points will be analyzed with mass cytometry.

Sponsors and collaborators

Lead sponsor

Martin Angst

Other

Registry information

Important dates

Study start
2012
Primary completion
2013
Study completion
2013
First posted
Jun 20, 2013
Registry last updated
May 4, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.