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OpenTrials
Active, Not Recruiting

NCT Number: NCT06157801

Evaluation of Hereditary Cancer Educational Videos

To learn if educational videos can help participants be more informed about hereditary cancers (ones that run in the family).

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Conditions

Hereditary Cancer

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

MD Anderson Cancer Center

Houston, Texas, 77030, United States

About this study

Primary Objective

Determine the impact of educational videos on:

  • Participant's hereditary cancer knowledge.
  • Participant's confidence to share hereditary cancer information with family members.

Secondary Objective

  • Determine impact of educational videos on participant's confidence to undergo hereditary cancer screening.
  • Identify opportunities to tailor and improve the educational video's content, style, and understandability per participant preferences and feedback.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Participants of The Harris Health System Lyndon B. Johnson (LBJ) Hospital outpatient oncology clinics (i.e., Gynecologic Oncology, Medical Oncology).
  • 18 years of age or older.
  • Speaks and/or reads English or Spanish.
  • Has a pathogenic or likely pathogenic variant (mutation) in BRCA1, BRCA2, MLH1, MSH2, MSH6, PMS2, and/or EPCAM on germline genetic testing.
  • Has a documented genetic testing results disclosure encounter (i.e. telephone call, follow-up appointment).

Exclusion criteria

  • No longer receives outpatient care at LBJ Hospital at time of recruitment.
  • Has only a variant of uncertain significance in BRCA1, BRCA2, MLH1, MSH2, MSH6, PMS2, and/or EPCAM.
  • Has only a pathogenic or likely pathogenic variant in gene other than BRCA1, BRCA2, MLH1, MSH2, MSH6, PMS2, or EPCAM.
  • Is unwilling, unable, or requires a legally authorized representative to provide informed consent.

Treatment and study plan

Interview Study

Behavioral

All study participants will have the following demographic information collected from their medical records:

  • Sex (Male/Female/Other)
  • Date of birth
  • Preferred language (English/Spanish)
  • Health insurance status (for example: private insurance, HCHD "gold card")
  • Cancer diagnosis (if yes: cancer type/organ, date of pathology diagnosis)
  • Genetic testing result (gene with pathogenic/likely pathogenic variant)
  • Date of genetic testing result
  • Date of documented result disclosure.

survey study

Behavioral

All study participants will have the following demographic information collected from their medical records:

  • Sex (Male/Female/Other)
  • Date of birth
  • Preferred language (English/Spanish)
  • Health insurance status (for example: private insurance, HCHD "gold card")
  • Cancer diagnosis (if yes: cancer type/organ, date of pathology diagnosis)
  • Genetic testing result (gene with pathogenic/likely pathogenic variant)
  • Date of genetic testing result
  • Date of documented result disclosure.

Primary outcomes

  1. Hereditary Cancer Multidimensional Measure of Informed Choice Questionnaires

    Time frame: through study completion; an average of 1 year

    Hereditary Cancer Multidimensional Measure of Informed Choice (MMIC)

    Knowledge Score scale: (1-8) true or false

Sponsors and collaborators

Lead sponsor

M.D. Anderson Cancer Center

Other

Registry information

Important dates

Study start
2024
Primary completion
2027
Study completion
2027
First posted
Dec 6, 2023
Registry last updated
Mar 4, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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