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NCT Number: NCT06685523

Evaluation of Fractalkine and Its Receptor in Peri-implantitis

In this study, mechanical debridement group, Er:YAG laser group and diode laser group will be compared in terms of reducing peri-implant sulcus depth in the treatment of peri-implantitis.

Recruiting

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Key information

Conditions

Peri-implantitis Mouth Diseases Periodontal Diseases Stomatognathic Diseases

Age range

40 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Kırıkkale University, Faculty of Dentistry, Department of Periodontology

Kirikkale, 71000, Turkey (Türkiye)

Location status: Recruiting

Location contact

Musa Bulut, Staff

CONTACT

[email protected]

+90-552-784-71-00

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Probing depth of 4-6 mm, bone loss of at least 2 mm on X-ray and presence of inflammatory symptoms in soft tissue
  • No systemic disease that may affect the outcome of the treatment
  • Patients with healthy periodontium or patients with completed periodontal treatment
  • Individuals at least 6 months after prosthesis loading on the implant
  • Individuals who do not require further surgery for the treatment of peri-implantitis
  • Implants with at least 2 mm keratised gingiva
  • Individuals aged 40-60 years

Exclusion criteria

  • Individuals undergoing radiation therapy
  • Individuals who smoke and drink alcohol
  • Individuals in pregnancy or lactation
  • Individuals who have received antibiotic treatment in the last three months
  • Individuals with parafunctional habits

Treatment and study plan

Subgingival Debridement

Procedure

To be applied 1 times (0. days)

Er:YAG laser decontamination

Procedure

To be applied 3 times

Diyot laser decontamination

Procedure

To be applied 3 times

Primary outcomes

  1. Probing depth, clinical attachment loss

    Time frame: sixth month

    Measurement will be made with a periodontal probe. The unit of measurement is millimetre. The primary outcome measures are interrelated.

Secondary outcomes

  1. gingival index, plaque index, sulcus blood index

    Time frame: sixth month

    The 0,1,2,3 point system for index measurements is currently used in periodontology. These scores will be used in secondary outcome measures.

Study contacts

Contact information is provided by the study sponsor or research team.

Kubilay Barış, Dr.

CONTACT

[email protected]

+90-0553-973-64-77

Sponsors and collaborators

Lead sponsor

Kubilay BARIŞ

Other

Registry information

Official study title

Evaluation of Fractalkine and Its Receptor in the Non-Surgical Treatment of Peri-implantitis

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Nov 12, 2024
Registry last updated
Nov 12, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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