Evaluation of Flexofytol® PLUS in Hand Joint Chronic Dyscomfort.

Inclusion criteria

• Older dan 45 years old,
• With hand joint chronic discomfort,
• Regularly uses of paracetamol or NSAIDs to manage pain,
• Painful symptoms must have been present for more than 6 months,
• The patient assesses their pain on a visual pain scale and must be greater than 4 out of 10 over the last 48 hours.

Exclusion criteria

• Related to previous and associated treatments:

• Corticosteroids injection in the 3 previous months, whatever the joint concerned,
• Use of Slow-acting drugs for OA and/or dietary supplements taken within less than 6 months prior to the study (ex: chondroitin sulfate, diacerein, soy and avocado unsaponifiables, oxaceprol, granions de cuivre, glucosamine, phytotherapy or homeopathy for hand joint discomfort..),
• Anticoagulant (coumarinic) treatment and heparin,
• General corticotherapy in the 3 previous months,
• Contraindication to paracetamol, curcumin, boswellia and NSAID's.
• Related to associated pathologies:

• Patient suffering from serious associated illness (liver failure, kidney failure, non-controlled cardiovascular diseases...),
• The patient has rheumatoid arthritis or gout,
• The patient has a bile obstruction.
• Related to patient:

• Pregnant or breastfeeding women.