Evaluation of Finastride Effect in Different Dosage on the Amount of Perioperative Bleeding in Transurthral Resection of Prostate

Preoperative use of finastride will decrease the amount of perioperative blood loss during and after TURP

The effect of finastride on decreasing the amount of perioperative blood loss during and after TURP is dose dependent

Finastride will decrease microvascular density in prostate tissue and this effect is dose dependent

Completed

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Key information

Conditions

Benign Prostate Hyperplasia Genital Diseases Genital Diseases, Male Male Urogenital Diseases Prostatic Diseases Prostatic Hyperplasia Urogenital Diseases

Age range

50 year and older

Sex eligibility

Male

Study type

Interventional

Phase

Phase 2 / Phase 3

Primary location

Faghihi Hospital

Shiraz, Fars, 71344, Iran

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients with BPH that require TURP

Exclusion criteria

Previous prostate surgery
Prostate Cancer
Coagulopathy
The use of NSAIDs, Anticoagulants, Antiplatelet drugs
CRF/ESRD

Treatment and study plan

TURP

Procedure

Transurthral resection of prostate

Primary outcomes

Perioperative Hb Drop

Time frame: 24 hours after surgery

Sponsors and collaborators

Lead sponsor

Shiraz University of Medical Sciences

Other

Registry information

Acronym: TURP

Important dates

Study start: 2012
Primary completion: 2013
Study completion: 2013
First posted: Jun 25, 2012
Registry last updated: Apr 20, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed