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Completed

NCT Number: NCT03973385

Evaluation of Efficacy of Cryotherapy for Skin Anesthesia During Arterial Puncture

the purpose of this study is to evaluate the cryotherapy effect by vapocoolant spray to reducing pain during puncture for artérial blood gas

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Key information

Conditions

Cryotherapy Effect

Age range

18 year–120 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Hopital Nord Franche-Comte, Belfort, France

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About this study

Blood gas analysis by arterial puncture is the Gold Standard in the assessment of a patient's acidbase status and oxygenation. This procedure, which can be repeated depending on the clinical condition of patient, is however associated with a potentially painful experience for patients.

The known anesthetic properties of cold can be an interesting alternative to evaluate in the reduction of pain induced during arterial puncture for gas analysis in critically il patients.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All adult patients (age≥18 years) hospitalized in Intensive Care Unit
  • Patient requiering arteriale puncture for ABG
  • A négative score of CAM ICU scale
  • Patient with a score to visual analog scale < or equal 30mm
  • Securité sociale affiliated
  • consentement

Exclusion criteria

  • patient undergoing mechanical ventilation
  • patient with arterial catheter
  • patient with arterio veinius fistul
  • patient receiving topical anesthesic at least 2 h before the puncture
  • patient with cutaneous lesion (zone of puncture)
  • Raynaud Syndrom
  • cold sensibility
  • Allen test negative
  • pregnant
  • legal guardianship

Treatment and study plan

Cryotherapy

Device

patients recieving cryotherapy for skin anesthesia for artérial blood gas

Primary outcomes

  1. Pain during arterial puncture

    Time frame: immediately after puncture

    Pain will be assessed with the visual analog scale (numeric value go 0 to 100 millimeters and representing intensity of pain from "no pain" to "worst pain imaginable"(1)

Secondary outcomes

  1. Ease to performing Arterial Blood Gas (ABG) sampling

    Time frame: immediately after puncture

    Ease to performing ABG sampling will be evaluated by i)the number of punctures necessary to obtain a sample of at least 1ml of arterial blood, ii) the delay between the first arterial puncture, and obtaining a sample.

Sponsors and collaborators

Lead sponsor

Versailles Hospital

Other

Registry information

Official study title

Evaluation of Efficacy of Cryotherapy for Skin Anesthesia During Arterial Puncture for Blood Gas in Critically Ill Patients. SNOW Study

Acronym: SNOW

Important dates

Study start
2020
Primary completion
2021
Study completion
2022
First posted
Jun 4, 2019
Registry last updated
Jul 7, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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