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NCT Number: NCT06913478

Evaluation Of Effect of Axial Length on Cup-To-Disc Ratio Among Non- Glaucomatous Hypertensive Patients

This observational cross-sectional study aims to compare the effect of axial length on the cup-to-disc ratio in non-glaucomatous hypertensive patients. Data will be collected from Khursheed Begum Eye Hospital and LRBT Hospital, with a sample size of 104 participants. A purposive sampling technique will be used.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Alshifa eye clinic Ali Pur chattha

Guiranwala, Punjab Province, Pakistan

About this study

Patients aged 18-70 years with systemic hypertension for at least one year and normal intraocular pressure will be included. Exclusion criteria include glaucoma, high myopia, hyperopia, ocular surgery, trauma, and optic nerve diseases. Axial length will be measured using optical biometry or A-scan ultrasonography, while the cup-to-disc ratio will be assessed through fundus examination using a slit lamp biomicroscope with a +90D lens or optical coherence tomography (OCT). Data will be meticulously documented, including patient demographics and medical history. The study will be completed within six months after approval, ensuring accurate and standardized measurements for reliable results.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Male and female patients diagnosed with systemic hypertension for at least 1 year.
  • Age between 18-70 years.
  • Normal intraocular pressure (IOP<-21mmhg)
  • Axial length between 21mm and 26mm (to exclude extreme refractive errors)

Exclusion criteria

  • History of glaucoma or ocular hypertension.
  • High myopia (<-6.00 D) or hyperopia (>+6.00D).
  • History of ocular surgery, trauma, or retinal diseases.
  • Any optic nerve diseases.

Treatment and study plan

Primary outcomes

  1. Axial length measured by biometry and CD ratio by slitlamp

    Time frame: 12 Months

    The axial length, measured in millimeters, is defined as the distance from the anterior surface of the cornea to the retinal pigment epithelium. The axial length can be measured using either ultrasound biometry (accomplished via direct contact or immersion) or optical biometry

Sponsors and collaborators

Lead sponsor

Superior University

Other

Registry information

Important dates

Study start
2025
Primary completion
2025
Study completion
2026
First posted
Apr 6, 2025
Registry last updated
Apr 6, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.