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OpenTrials
Completed

NCT Number: NCT02220556

Evaluation of Different Analysis Methods for Circulating Tumor Cells, Circulating Endothelial Cell, and Circulating Tumor DNA in Patient Followed for a Tumoral Pathology

Fifteen cohorts will be opened. Each cohort will explore one analysis method and/or tumoral type. Up to 50 patient can be included into each cohort.

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Key information

Conditions

Solid Tumor, Adult

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Institut Curie, Paris, France

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Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18 years old or more
  • Performance status from 0 to 4
  • Patient treated followed for histologically confirmed solid tumor type of any of these localization : breast, prostate, uterus, ovary, colon, lung, head and neck, melanoma.
  • Informed consent form signed.

Exclusion criteria

  • Patient with history of other invasive cancer within 5 years.
  • Patient treated for any non-invasive cancer
  • Patient individually deprived of liberty or placed under the authority of a tutor
  • Geographical condition potentially preventing compliance with the study protocol.

Treatment and study plan

blood sampling

Procedure

Primary outcomes

  1. CTC, CEC or ctDNA incidence

    Time frame: 3 years

    number of CTC or CEC in 7.5ml of blood

Secondary outcomes

  1. CTC and CEC molecular characterization

    Time frame: 3 years

    This outcome is self-explanatory.

  2. Circulating tumor DNA (ctDNA) detection and quantification

    Time frame: 3 years

    plasma mutation detection (number of copy)

Sponsors and collaborators

Lead sponsor

Institut Curie

Other

Registry information

Acronym: CTC-CEC-ADN

Important dates

Study start
2010
Primary completion
2018
Study completion
2018
First posted
Aug 20, 2014
Registry last updated
Aug 8, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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