Evaluation of Diagnosis and Treatment Methods in Corrosive Esophagitis: A 26-Year Experience-Based Algorithm

This study aims to evaluate the diagnosis and treatment methods for corrosive esophagitis based on 26 years of clinical experience. It will retrospectively analyze patient records to identify patterns in clinical outcomes, complications, and the effectiveness of treatment strategies. The study focuses on optimizing patient care by proposing a diagnosis and treatment algorithm that can guide future clinical practices. Data will be collected from hospital archives and electronic health records, covering cases of corrosive esophagitis managed at Ondokuz Mayıs University between 1998 and 2024.

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Key information

Conditions

Esophageal Diseases Digestive System Diseases Gastrointestinal Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Ondokuz Mayıs University Faculty of Medicine

Samsun, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients diagnosed with corrosive esophagitis due to corrosive substance ingestion.
Hospitalized and treated at Ondokuz Mayıs University Thoracic Surgery Department.
Patients who underwent clinical, laboratory, and radiological evaluations to confirm the diagnosis.
Patients who were monitored and met follow-up criteria during their treatment.
Patients above 18 years of age

Exclusion criteria

Patients under 18 years of age.
Patients who refused hospitalization or treatment.
Patients who ingested non-corrosive or non-toxic substances (verified by the Ministry of Health Poison Information Center).
Patients lost to follow-up or did not complete follow-up requirements.
Patients with incomplete data during the diagnostic or treatment process.

Treatment and study plan

Routine Care for Corrosive Esophagitis

Other

This is an observational study, so participants are not assigned interventions. However, the study investigates the outcomes of patients diagnosed with corrosive esophagitis who received routine clinical care. The exposure of interest includes diagnostic and treatment procedures such as endoscopic evaluation (Zargar classification), proton pump inhibitors, corticosteroid therapy, and surgical interventions for complications like strictures. The outcomes and clinical data collected reflect routine care practices over 26 years.

Primary outcomes

Incidence of Esophageal Stricture, Perforation, and Other Related Complications

Time frame: Within 1 month after hospital admission

The number of patients who develop esophageal strictures, perforation, or other complications within 1 month post-admission will be recorded.

Sponsors and collaborators

Lead sponsor

Caner İşevi, MD

Other

Registry information

Official study title

Evaluation of Diagnosis and Treatment Methods in Corrosive Esophagitis: Analysis of a 26-Year Experience-Based Algorithm

Important dates

Study start: 2025
Primary completion: 2025
Study completion: 2025
First posted: Feb 10, 2025
Registry last updated: May 21, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed