Institut National d'Oncologie
Rabat, 10100, Morocco
NCT Number: NCT04248634
After rectal resection for cancer of the lower rectum, the restoration of continuity is done by a colo-anal anastomosis with a protective ileostomy. However, the ileostomy is very little accepted by patients. It is associated with significant morbidity and a deterioration in the quality of life.
Delayed colo-anal anastomosis has been proposed as an alternative to direct colo-anal anastomosis with a protective ileostomy. The theoretical advantage of this technique is to reduce the risk of anastomotic leaks and to avoid ileostomy.
In this study, the investigators will retrospectively evaluate the short and midterm results of this technique.
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Notify Me18 year and older
All sexes
Observational
Rabat, 10100, Morocco
After rectal resection for cancer of the lower rectum, the restoration of continuity is done by a colo-anal anastomosis with a protective ileostomy. The latter reduces the risk and severity of clinical anastomotic fistulas. However, the ileostomy is very little accepted by patients. It is associated with significant morbidity reaching up to 30% of patients, a deterioration in the quality of life and the need for a second surgery to restore digestive continuity. And specifically in low-income countries, ostomy bags are expensive and are not reimbursed, and therefore constitute a heavy burden for Moroccan patients.
In order to overcome these drawbacks, delayed colo-anal anastomosis has been proposed as an alternative to direct colo-anal anastomosis with a protective ileostomy. This technique consists of externalizing the colon in the first stage by the transanal route, without creating an ileostomy, and waiting a week for the creation of the anastomosis. The theoretical advantage of this technique is to reduce the risk of anastomotic leaks and to avoid ileostomy. Several studies have shown encouraging results in the short and midterm, and it is listed among the technical options in the French recommendations for the management of rectal cancer.
In this study, the investigators will retrospectively evaluate the short and midterm results of this technique.
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Colo-anal anastomosis performed in two surgical steps:
Step two: after 7 days, the excess colon is resected and the colo-anal anastomosis is created.
Time frame: 90 days
The rate of patients who required a stoma creation at 90 days
Time frame: 90 days
Rates of perineal complications at 90 days after surgery
Time frame: 90 days
Rate of complications according to Clavien-Dindo grading
Time frame: 12 months
Continence score according to the Low anterior resection syndrom score (LARS). Score from 0 to 42 (0-20 No LARS / 21-29 Minor LARS / 30-42 Major LARS). Higher score indicates worse outcome
Time frame: 12 months
Quality of life using the EORTC QLQ30 score at 6 and 12 months
Institut National d'Oncologie, Morocco
Other Gov
Short and Midterm Results of Delayed Colo-anal Anastomosis After Rectal Resection
Acronym: ACAD
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