the First Affiliated Hospital of Henan University of Chinese Medicine
Zhengzhou, Henan, 450000, China
Location status: Recruiting
NCT Number: NCT07632352
Based on the bioholographic theory, this study preliminarily explores the clinical efficacy of hand acupuncture in treating acute exacerbation of bronchial asthma and evaluates its immediate anti-asthmatic effect, so as to provide a new therapeutic strategy for the clinical management of bronchial asthma.
Interested in participating?
Request Info18 year and older
All sexes
Interventional
Not applicable
Zhengzhou, Henan, 450000, China
Location status: Recruiting
This study adopted a randomized controlled trial design, with patients in the acute exacerbation phase of bronchial asthma as the research subjects. A total of 72 patients who met the inclusion criteria were randomly divided into the acupuncture group and the control group in a 1:1 ratio. The control group received standard Western medicine treatment, while the acupuncture group was given acupuncture treatment based on biological holography theory in addition to the standard Western medicine treatment. The acupoints selected were Kechuan point, New Kechuan point, and Yuji point. The treatment was administered once a day for 20 minutes each time, for 5 consecutive days, with a 3-month follow-up. The therapeutic efficacy of manual acupuncture in treating acute exacerbation of bronchial asthma was evaluated with indicators including symptom and sign scores, pulmonary function, ACT , mMRC , Mini-AQLQ scale, serum interleukin-4 (IL-4), serum eotaxin and specific immunoglobulin E (SIgE). In addition, the underlying therapeutic mechanism was preliminarily explored to formulate a technical protocol for rapid anti-asthma acupuncture, laying a foundation for long-term and objective efficacy evaluation of this therapy.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
The acupoints selected were Kechuan point, New Kechuan point, and Yuji point. The treatment was administered once a day for 20 minutes each time, for 5 consecutive days.
Evaluate and manage in accordance with the Chinese Expert Consensus on Assessment and Management of Acute Exacerbation of Bronchial Asthma issued by the Asthma Group of the Chinese Thoracic Society, Chinese Medical Association in 2018 and the Guidelines for the Prevention and Treatment of Bronchial Asthma (2020 ).
Time frame: After treatment on Day 5 and follow-up at 1, 2 and 3 months
PEF will be used to assess pulmonary function
Time frame: After treatment on Day 5 and follow-up at 1, 2 and 3 months
The ACT score consists of 5 questions, each scored from 1 to 5 points, with a total score ranging from 5 to 25 points; lower scores indicate more severe symptoms.
Time frame: After treatment on Day 5 and follow-up at 1, 2 and 3 months
FEV1%pred will be used to assess pulmonary function
Time frame: After treatment on Day 5 and follow-up at 1, 2 and 3 months
It includes six symptoms: cough, expectoration, chest tightness, wheezing, shortness of breath and wheeze. Scores of 0, 3, 6 and 9 are assigned according to the severity of symptoms, with higher scores corresponding to more severe symptoms.
Time frame: After treatment on Day 5 and follow-up at 1, 2 and 3 months
It consists of 15 questions, each scored on a scale from 1 to 7 based on the severity of symptoms and their degree of impact. A score of 1 indicates no symptoms or no adverse impacts, while a score of 7 stands for severe symptoms or substantial impairment. Lower total scores correspond to a higher quality of life.
Time frame: After treatment on Day 5 and follow-up at 1, 2 and 3 months
Scores range from 0 to 4 based on the severity of dyspnea, with higher scores indicating more severe symptoms.
Time frame: After treatment on Day 5
Detect the level of IL-4 in peripheral blood
Time frame: After treatment on Day 5
Detect the level of Eotaxin in peripheral blood
Time frame: After treatment on Day 5
Detect the level of IgE in peripheral blood
Contact information is provided by the study sponsor or research team.
Henan University of Traditional Chinese Medicine
Other
Evaluation of Clinical Effect of Acupuncture on Acute Exacerbation of Bronchial Asthma Based on Biological Holography Theory
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT07620691
Asthma, Bronchial Asthma
Saskatoon, SK - Saskatchewan, Canada
View Trial DetailsNCT04157361
Asthma, Bronchial Asthma
Olomouc, Czechia
View Trial DetailsNCT07326995
Asthma, Bronchial Asthma
Nanchang, Jiangxi, China
View Trial DetailsNCT07324707
Asthma, Bronchial Asthma
Nanchang, Jiangxi, China
View Trial Details