Evaluation Of Cardiovascular Health Outcomes Among Survivors 2

Primary Objective:

• To determine the efficacy of the Healthy Hearts eHealth intervention compared to standard of care for improving screening echocardiogram adherence in childhood cancer survivors.

Secondary Objective

• To determine the efficacy of the Healthy Hearts eHealth intervention compared to standard of care for improving mediators of screening echocardiogram adherence in childhood cancer survivors.

After consenting, participants will complete a survey that will take about 15-20 minutes to complete. After this survey, they will be randomly assigned to participate in the Healthy Hearts eHealth Intervention or to receive standard educational materials about hearth health screening.

All participants will receive the Standard of Care (SOC) materials delivered via the Computerized Intervention Authoring System (CIAS) platform (i.e., a personalized survivorship care plan and educational materials regarding cardiomyopathy risk and need for screening). In addition to the SOC materials received by controls, the Healthy Hearts eHealth intervention arm will receive CIAS platform delivered Motivational Interview (MI), including scripted interaction with an avatar, video vignettes, and patient testimonials

Inclusion criteria

• Childhood Cancer Survivor Study (CCSS) Participants
• Age ≥26 years
• Treated with cumulative doxorubicin equivalent anthracycline doses ≥100 mg/m2 with any/no radiation, or ≥15 Gy chest radiation with any/no anthracyclines
• No history of cardiomyopathy
• Has not had an echocardiogram in the previous 5 years
• Has a history of successful completion of CCSS surveys
• English-Speaking
• Has not been enrolled in ECHOS-1 (pilot)

Exclusion criteria

• Currently participating in a long-term follow-up program that provides risk-based screening