Evaluation of Antiproliferative Effects of Arimidex in Ductal Lavage Fluid in Patients With Breast Cancer

The goal of this study is to evaluate antiproliferative effects of Arimidex in ductal lavage fluids of Breast Cancer patients.

Breast cancer is the leading cause of cancer incidence and the second leading cause of cancer mortality in women. Breast duct fluid provide biomarkers to aid in risk assessment of developing breast cancer.

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Key information

Conditions

Breast Cancer Breast Diseases Breast Neoplasms Neoplasms Neoplasms by Site Skin Diseases Skin and Connective Tissue Diseases

Sex eligibility

Female

Study type

Observational

Primary location

UT MD Anderson Cancer Center

Houston, Texas, 77030, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patient must have a history of breast cancer.
Patient must be scheduled to receive standard treatment with Arimidex for adjuvant hormonal management.
Patient must be willing to undergo a duct lavage.
Patient must sign an Informed Consent.

Exclusion criteria

None.

Treatment and study plan

Ductal Lavage Fluid Collection

Procedure

Procedure of inserting a small catheter into the ductal openings in the nipple and washing out cells from inside the duct.

Primary outcomes

Number of Patients with Antiproliferative Effects of Arimidex

Time frame: Study duration 4 years

Biomarker modulation study on effects of Armimidex in ductal lavage fluid from evaluable epithelial cells specimen.

Sponsors and collaborators

Lead sponsor

M.D. Anderson Cancer Center

Other

Registry information

Important dates

Study start: 2002
Primary completion: 2006
Study completion: 2006
First posted: Sep 23, 2010
Registry last updated: Jul 30, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed