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OpenTrials
Completed

NCT Number: NCT06782438

Evaluation of an Artificial Intelligence Algorithm Reducing Noise on Fast Whole-body Bone Tomoscintigraphy Acquisitions Recorded by a 360 Degree Cadmium-Zinc-Tellurid Camera

Recently, artificial intelligence algorithms reducing noise by deep learning have been developed with application to SPECT and PET images.

Many studies have reported the possibility of reducing the recording time in bone scintigraphy by applying artificial intelligence algorithms reducing noise

Completed

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Key information

Conditions

Age range

18 year–99 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Nuclear Medicine Department

Vandœuvre-lès-Nancy, 54511, France

About this study

Only two studies compared images denoised by a Deep Learning algorithm to those denoised by conventional filters (Gaussian and median filters). The first study was conducted only on patients, without phantom analysis and without taking into account the size of the lesions. The second study included an analysis on phantom and patients, but with application to planar images rather than to SPECT images that are increasingly used today

The hypothesis of our study conducted on phantom and patients is that an artificial intelligence algorithm reducing noise could replace the conventional filters usually used in bone SPECT for the denoising of scintigraphic images.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients who had a whole-body thee dimensions bone scan for rheumatological or oncological indications.

Exclusion criteria

Patients opposed to the use of their data

Treatment and study plan

Artificial intelligence algorithm

Other

to apply an artificial intelligence algorithm to treat the imaging

Primary outcomes

  1. To compare imaging treated by the intelligence artificial algorithm with imaging treated with the traditionnal filter artificial algorithm

    Time frame: one day

    Quantification value on imaging measured with intelligence artificial algorithm compared with quantification value measured with conventional filter

Sponsors and collaborators

Lead sponsor

Central Hospital, Nancy, France

Other

Registry information

Acronym: IATOS2

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jan 17, 2025
Registry last updated
Jun 25, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.