Evaluation of a Theory-Driven Manualized Approach to Improving New Learning and Memory in MS

The purpose of this research study is to investigate the effectiveness of a memory enhancement technique in persons with Multiple Sclerosis (MS). The study is designed to research how well this technique can help people with MS improve their memory and their ability to function better in everyday life.

Inclusion criteria

• Diagnosis of Multiple Sclerosis
• Ability to read and speak English fluently
• Difficulties with learning and memory skills

Exclusion criteria

• Prior diagnosis of stroke or other neurological injury/disease
• Flare up of symptoms within a month of study participation
• History of significant psychiatric illness (e.g., bipolar disorder, schizophrenia, psychosis) or current diagnosis of Major Depressive Disorder, Schizophrenia, Bipolar Disorder I or II
• Current significant alcohol or substance abuse
• Taking exclusionary medication (study team will review medications)

For Optional MRI:

• Pacemaker or other implanted electrical device, brain stimulator, aneurysm clip (metal clips on the wall of a large artery), metallic prostheses (including metal pins and rods, heart valves, and internal hearing aids [cochlear implants]), permanent eyeliner, implanted delivery pumps, or shrapnel fragments.
• Dental implants
• Left-handed