Evaluation by MRI of Anal Canal Cell Carcinoma: is There Predictive Factor?

Anal canal cell carcinoma is a very rare cancer but well treated. If the morphological test are well established in the initial evaluation, it's not the case of the follow up evaluation particularly by MRI.About 1/3 of patient decline with metastatic relapse during the follow up of these patients.It appears that clinical regression seen precociously is a predictive factor of survival without relapse. But there 's no study confirming that point.

This context takes us to evaluate if there is a predictive factor in MRI to final clinical result.

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Key information

Conditions

Anal Carcinoma Anus Diseases Anus Neoplasms Colorectal Neoplasms Digestive System Diseases Digestive System Neoplasms Gastrointestinal Diseases Gastrointestinal Neoplasms Intestinal Diseases Intestinal Neoplasms Neoplasms Neoplasms by Site Rectal Diseases Rectal Neoplasms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Groupe Hospitalier Paris Saint Joseph

Paris, Île-de-France Region, 75014, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

patient with anal canal cell carcinoma histologically proved
patient with initial MRI and follow up MRI in Hospital St Joseph's radiology yard.
patient for whom a radio chemotherapy treatment decision was taken.

Exclusion criteria

patients with already metastatic lesions

Treatment and study plan

MRI sequence

Diagnostic Test

several MRI sequence before and after contrast product injection.

Primary outcomes

Distance with regard to the anal margin

Time frame: maximum of 6 years after the initial MRI

tumor position
initial tumor size

Time frame: maximum of 6 years after the initial MRI

Maximal tumoral size in the cranio-caudal plan in cm
presence of nodal status

Time frame: maximum of 6 years after the initial MRI

presence of nodal status in inguinal region

Sponsors and collaborators

Lead sponsor

Fondation Hôpital Saint-Joseph

Other

Registry information

Important dates

Study start: 2017
Primary completion: 2017
Study completion: 2017
First posted: Mar 19, 2018
Registry last updated: Mar 22, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed